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The paper identifies a pre-transplant γδ T-cell effector signature associated with kidney allograft rejection using multi-omics data from transplant recipients.

The paper evaluates spike sorting errors in awake mice using ground-truth data and finds that false negatives increase significantly during bursting and spike overlaps, challenging conventional benchmarks.

The paper shows that greater intraspecific morphological variation in bulbuls predicts broader ecological niches and larger geographic ranges.

The paper shows that most hnRNP proteins are excluded from DNA double-strand breaks, with hnRNPH1's exclusion dependent on its GYR domain and independent of recruitment pathways.

This study shows FoxO1 and HNF1α work together to change nucleosome structure and stability to activate transcription.

This study investigates visual plasticity in surgeonfishes by analyzing opsin gene expression across 22 species, revealing a deep phylogenetic split in visual systems that predates ecological diversification.

This paper shows that delivering the anti-TGFβ peptide P144 via CAR-T cells enhances their efficacy in mesothelioma by recruiting neutrophils and remodeling the tumor microenvironment.

The paper identifies germ granule-like amyloid/RNA condensates in rat epididymal spermatozoa that exhibit prion-like propagation activity, suggesting a non-Mendelian mechanism for transmitting environmental information to offspring.

This study uses spatial transcriptomics to identify a hypoxia-associated SPP1-enriched microenvironment in pediatric TB granulomas that may contribute to incomplete bacterial clearance.

This paper introduces ultradeep OCT to image deep brain structures with improved depth and resolution, demonstrating its potential for studying neurodegenerative diseases.

This study identifies spatio-temporal dynamics and ecological niche factors influencing Theileria equi infection in Portugal using field-surveillance data and environmental variables.

This study shows HOT1 functions as a homodimer to maintain an ALT-permissive chromatin state at telomeres.

This study uses functional ultrasound imaging in marmosets to show that intra-call prosodic features influence large-scale cortical dynamics during vocal interactions.

This study identifies NRT2.2 as the primary nitrate transporter in Nannochloropsis oceanica and shows its critical role in nitrate uptake and carbon-nitrogen balance.

This study compares five methods for detecting the urobiome in urine samples, finding that shotgun metagenomic sequencing provides the broadest species-level view, while culture methods have specific strengths.

This study identifies Msp300 as a novel interactor of Atg8a in Drosophila, linking autophagy to nuclear architecture through the LINC complex.

This study shows that sub-anesthetic ketamine reduces dyskinesia caused by D2R-like receptor agonists but not D1R-like receptor agonists in L-DOPA-primed rats.

This study uses serial intravascular labeling to show dynamic changes in decidual NK cell residency and T-bet expression during pregnancy.

This study identifies DPYD's role in sleep regulation through glial lipid metabolism and myelination across species, linking genetic variants to oligodendrocyte-specific control.

This study shows that the 5-HT6 receptor in pancreatic beta cells, localized to cilia, enhances insulin secretion, highlighting ciliary localization as a key determinant of GPCR function.