Author

E. Hawkins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Plant Biology· 2 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 5 Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 3 Assay:imaging· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2

Frequent Co-Authors

I. Kong· 3 shared A. Watson-Lazowski· 2 shared B. Fahy· 2 shared D. Duarte· 2 shared D. Seung· 2 shared F. J. Warren· 2 shared J. Chen· 2 shared J. E. Barclay· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

I. Kong

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Anti-TGFβ peptide P144 augments CAR-T cell efficacy through neutrophil recruitment and TME remodeling in malignant mesothelioma

R. Bugda, E. Hawkins, G. Box, F. Secchiari, C. Leboreiro Babe, R. S. Tan, P. Dimou, R. R. D'Souza, Astero Klampatsa

This paper shows that delivering the anti-TGFβ peptide P144 via CAR-T cells enhances their efficacy in mesothelioma by recruiting neutrophils and remodeling the tumor microenvironment.

bioRxiv · Nov 3, 2026 · PreprintImmunology

An immunohistochemical atlas of necroptotic pathway expression

S. Chiou, A. Al-Ani, Y. Pan, K. Patel, I. Kong, L. Whitehead, A. Light, S. Young, M. Barrios, C. Sargeant, P. Rajasekhar, L. Zhu, A. Hempel, A. Lin, J. Rickard, , A. L. Samson

The paper develops automated immunohistochemistry protocols to detect necroptotic pathway proteins in mouse and human tissues, revealing heterogeneity and disease-related changes in expression.

bioRxiv · Oct 31, 2023Cell Biology

Comparison of spontaneous recurrent seizures in rats following status epilepticus induced by organophosphate paraoxon, DFP, and sarin

R. Blair, E. Hawkins, L. Pinchbeck, R. DeLorenzo, L. Deshpande

This study evaluates spontaneous recurrent seizures in rats after status epilepticus induced by organophosphate agents, finding hippocampal neuronal loss and mossy fiber sprouting associated with chronic epilepsy.

bioRxiv · May 10, 2023 · PreprintPharmacology & Toxicology

OPS-γδ: allogeneic opsonin-secreting γδT cell immunotherapy for solid tumours mediates direct and bystander immunity

D. Fowler, M. Barisa, A. Southern Navarrete, C. Nattress, E. Hawkins, E. Vassalou, A. Kanouta, J. Counsell, E. M. Rota, P. Vlckova, B. Draper, C. J. Tape, K. Chester, J. Anderson, J. Fisher

OPS-γδ cells, engineered to secrete opsonins and stabilized IL15, show enhanced cytotoxicity and bystander activation for solid tumor control.

bioRxiv · Oct 23, 2022 · PreprintImmunology

The plastidial protein MRC promotes starch granule initiation in wheat leaves but delays B-type granule initiation in the endosperm

J. Chen, Y. Chen, A. Watson-Lazowski, E. Hawkins, J. E. Barclay, B. Fahy, R. Denley-Bowers, K. Corbin, F. J. Warren, A. Blennow, C. Uauy, D. Seung

This study identifies MRC's organ-specific roles in regulating starch granule initiation in wheat leaves and endosperm, showing it promotes leaf granules but delays endosperm B-type granule initiation.

bioRxiv · Oct 7, 2022Plant Biology

STARCH SYNTHASE 4 is required for normal starch granule initiation in amyloplasts of wheat endosperm

E. Hawkins, J. Chen, A. Watson-Lazowski, J. Ahn-Jarvis, J. E. Barclay, B. Fahy, M. Hartley, F. J. Warren, D. Seung

This study investigates the role of STARCH SYNTHASE 4 (SS4) in wheat endosperm starch granule initiation, finding that SS4 deficiency causes compound granule formation and reduced starch content.

bioRxiv · Jan 29, 2021Plant Biology

The metalloproteinase inhibitor Prinomastat reduces AML growth,prevents stem cell loss and improves chemotherapy effectiveness

C. Pirillo, M. Haltalli, S. Gonzalez Anton, V. Tini, I. Kong, E. Hawkins, B. Falini, A. Marra, D. Duarte, C. Lo Celso

This study shows that prinomastat, an MMP inhibitor, reduces AML growth, prevents stem cell loss, and enhances chemotherapy effectiveness in a mouse model.

bioRxiv · Dec 1, 2020 · PreprintCancer Biology

Loss of erythroblasts in acute myeloid leukemia causes iron redistribution with clinical implications

M. Lopes, T. Duarte, M. J. Teles, L. Mosteo, S. Chacim, E. Aguiar, J. Pereira-Reis, M. Oliveira, A. M. N. Silva, N. Goncalves, G. Martins, I. Kong, M. Zethoven, S. Vervoort, S. Martins, , D. Duarte

The paper investigates iron metabolism in AML, finding that AML causes iron redistribution through erythroblast loss, leading to high TSAT and improved survival.

bioRxiv · Oct 26, 2020Cancer Biology