Author

N. K. Ryan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

L. M. Butler· 2 shared A. A. Shafi· 1 shared A. J. Hoy· 1 shared A. Sharp· 1 shared C. M. McNair· 1 shared D. Bogdan· 1 shared D. J. Lynn· 1 shared E. G. DeArment· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

L. M. Butler

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2 papers

Recent·Most cited

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer

S. Sardar, C. M. McNair, L. Ravindranath, S. N. Chand, W. Yuan, D. Bogdan, J. Welti, A. Sharp, N. K. Ryan, M. J. Schiewer, E. G. DeArment, T. Janas, X. A. Su, L. M. Butler, J. S. de Bono, , A. A. Shafi

This study identifies CBP/p300 as critical for DNA repair in prostate cancer and shows that targeting it enhances therapeutic response.

bioRxiv · May 7, 2024Cancer Biology

A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth

J. L. Gillis, J. A. Hinneh, N. K. Ryan, S. Irani, M. Moldovan, R. K. Shrestha, L.-E. Quek, A. J. Hoy, J. Holst, M. M. Centenera, I. G. Mills, D. J. Lynn, L. A. Selth, L. M. Butler

This study identifies a feedback loop between the androgen receptor and 6PGD that drives prostate cancer growth and shows that targeting both improves therapeutic efficacy.

bioRxiv · Sep 2, 2020Cancer Biology