Author

X. A. Su

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. A. Shafi· 1 shared A. M. Darnell· 1 shared A. Sharp· 1 shared B. T. Do· 1 shared C. Chidley· 1 shared C. M. McNair· 1 shared D. B. Sykes· 1 shared D. Bogdan· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. A. Shafi

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer

S. Sardar, C. M. McNair, L. Ravindranath, S. N. Chand, W. Yuan, D. Bogdan, J. Welti, A. Sharp, N. K. Ryan, M. J. Schiewer, E. G. DeArment, T. Janas, X. A. Su, L. M. Butler, J. S. de Bono, , A. A. Shafi

This study identifies CBP/p300 as critical for DNA repair in prostate cancer and shows that targeting it enhances therapeutic response.

bioRxiv · May 7, 2024Cancer Biology

Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

B. T. Do, P. P. Hsu, S. Y. Vermeulen, Z. Wang, T. Hirz, K. L. Abbott, N. Aziz, J. M. Replogle, S. Bjelosevic, J. Paolino, S. Nelson, S. Block, A. M. Darnell, R. Ferreira, H. Zhang, , M. G. Vander Heiden

The paper shows that nucleotide depletion and DNA replication stress drive cell fate transitions in hematopoietic systems by activating lineage-specific maturation genes.

bioRxiv · Aug 16, 2022Cancer Biology