Author

A. Al'Khafaji

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Brock· 1 shared A. Brown· 1 shared B. Liu· 1 shared C. Gutierrez· 1 shared C. J. Wu· 1 shared D. Dele-Oni· 1 shared D. Neuberg· 1 shared E. Brenner· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Brock

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Author profile →

2 papers

Recent·Most cited

ESCRT-dependent STING degradation curtails steady-state and cGAMP-induced signaling

M. Gentili, B. Liu, M. Papanastasiou, D. Dele-Oni, M. A. Schwartz, R. J. Carlson, A. Al'Khafaji, K. Krug, A. Brown, J. G. Doench, S. A. Carr, N. Hacohen

The paper identifies an ESCRT complex that degrades STING to suppress its signaling, showing its role in maintaining immune homeostasis.

bioRxiv · Sep 22, 2022 · PreprintImmunology

Expressed barcodes enable clonal characterization of chemotherapeutic responses in chronic lymphocytic leukemia

A. Al'Khafaji, C. Gutierrez, E. Brenner, R. Durrett, K. E. Johnson, W. Zhang, S. Li, K. J. Livak, D. Neuberg, A. Brock, C. J. Wu

This paper develops a method to study clonal responses to chemotherapy in CLL by combining barcoding with single-cell RNA sequencing, revealing that rare drug-tolerant clones dominate post-treatment populations.

bioRxiv · Sep 8, 2019Cancer Biology