Author

R. J. Carlson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

N. Hacohen· 2 shared A. Al'Khafaji· 1 shared A. Brown· 1 shared A. Radhakrishnan· 1 shared A. Singh· 1 shared B. Liu· 1 shared B. Y. Soong· 1 shared C. Bradfield· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

N. Hacohen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-cell image-based genetic screens systematically identify regulators of Ebola virus subcellular infection dynamics

R. J. Carlson, J. J. Patten, G. Stefanakis, B. Y. Soong, A. Radhakrishnan, A. Singh, N. Thakur, G. K. Amarasinghe, N. Hacohen, C. F. Basler, D. Leung, C. Uhler, R. A. Davey, P. C. Blainey

This study uses single-cell image-based CRISPR screens to identify host factors regulating Ebola virus infection, revealing new therapeutic targets like UQCRB and STRAP.

bioRxiv · Apr 6, 2024 · PreprintMicrobiology

ESCRT-dependent STING degradation curtails steady-state and cGAMP-induced signaling

M. Gentili, B. Liu, M. Papanastasiou, D. Dele-Oni, M. A. Schwartz, R. J. Carlson, A. Al'Khafaji, K. Krug, A. Brown, J. G. Doench, S. A. Carr, N. Hacohen

The paper identifies an ESCRT complex that degrades STING to suppress its signaling, showing its role in maintaining immune homeostasis.

bioRxiv · Sep 22, 2022 · PreprintImmunology

IRAK1-mediated coincidence detection of microbial signals licenses inflammasome activation

S. J. Vayttaden, M. Smelkinson, O. Ernst, R. J. Carlson, J. Sun, C. Bradfield, M. G. Dorrington, J. Liang, N. Bouladoux, R. A. Gottschalk, K.-S. Oh, G. Pegoraro, S. Ganesan, D. De Nardo, E. Latz, , I. D. C. Fraser

This study identifies IRAK1-mediated supramolecular organizing centers that coordinate multiple immune pathways to license inflammasome activation in response to microbial signals.

bioRxiv · Dec 26, 2019 · PreprintImmunology