Author

A. Cercek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Barlas· 2 shared K. Ganesh· 2 shared A. Boire· 1 shared A. E. Hendifar· 1 shared A. Elghouayel· 1 shared A. J. McRee· 1 shared A. L. Ho· 1 shared A. Luthra· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

A. Barlas

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Author profile →

3 papers

Recent·Most cited

Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients

B. Nguyen, C. Fong, A. Luthra, S. A. Smith, R. G. DiNatale, S. Nandakumar, H. Walch, W. K. Chatila, R. Madupuri, R. Kundra, C. M. Bielski, B. Mastrogiacomo, A. Boire, S. Chandarlapaty, K. Ganesh, , Varghes

The paper analyzes genomic data from 25,000 patients to identify associations between genomic alterations and metastatic patterns across 50 tumor types, finding chromosomal instability correlates with metastatic burden in some cancers.

bioRxiv · Jun 28, 2021Cancer Biology

Therapeutic targeting of SLC6A8 creatine transporter inhibits KRAS mutant and wildtype colon cancer and modulates human creatine levels

I. Kurth, N. Yamaguchi, C. Andreu-Agullo, H. S. Tian, S. Sridhar, S. Takeda, F. C. Gonsalves, J. M. Loo, A. Barlas, K. Manova-Todorova, R. Busby, J. C. Bendell, J. Strauss, M. Fakih, A. J. McRee, , S. F. Tavazoie

RGX-202 inhibits CRC growth by targeting SLC6A8 creatine transporter, reduces creatine and ATP levels, and shows efficacy in multiple tumor models and human trials.

bioRxiv · Apr 26, 2021Cancer Biology

A rectal cancer model establishes a platform to study individual responses to chemoradiation

K. Ganesh, C. Wu, K. P. O'Rourke, M. Adileh, B. C. Szeglin, I. Wasserman, M. R. Marco, M. Shady, Y. Zheng, W. R. Karthaus, H. H. Won, S.-H. Choi, R. A. Pelossof, A. Barlas, E. Pappou, , J. J. Smith

This study develops a rectal cancer organoid model that mimics patient tumor responses to chemoradiation and metastasis in mice.

bioRxiv · May 22, 2019 · PreprintCancer Biology