Author

A. C. Cole

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

C. M. Paulos· 2 shared G. B. Lesinski· 2 shared G. O. Rangel Rivera· 2 shared M. M. Wyatt· 2 shared A. S. Smith· 1 shared B. A. Aksoy· 1 shared C. J. Dwyer· 1 shared H. Knochelmann· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCancer Biology

C. M. Paulos

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Distinct host preconditioning regimens differentially impact the antitumor potency of adoptively transferred Th17 cells.

M. C. Wittling, H. M. Knochelmann, M. M. Wyatt, G. O. Rangel Rivera, A. C. Cole, G. B. Lesinski, C. M. Paulos

This study compares the effects of two host preconditioning methods on the antitumor activity of adoptively transferred Th17 cells, finding that total body irradiation enhances their efficacy more than chemotherapy.

bioRxiv · Dec 18, 2023Cancer Biology

The degree of T cell stemness differentially impacts the potency of adoptive cancer immunotherapy in a Lef-1 and Tcf-1 dependent manner.

G. O. Rangel Rivera, C. J. Dwyer, H. Knochelmann, A. S. Smith, B. A. Aksoy, A. C. Cole, M. M. Wyatt, J. E. Thaxton, G. B. Lesinski, C. M. Paulos

This study shows that varying levels of PI3Kδ pathway inhibition affect T cell stemness, with higher stemness improving cancer immunotherapy outcomes in multiple tumor models.

bioRxiv · Mar 8, 2023 · PreprintImmunology