Author

A. Churchyard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:plant (other)· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

J. Baum· 3 shared S. Wittlin· 2 shared A. C. Aguiar· 1 shared A. K. Lawong· 1 shared A. Kumar· 1 shared B. C. Fernandez· 1 shared B. Campo· 1 shared B. Crespo-Fernandez· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMicrobiology

J. Baum

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A fast-killing tyrosine amide ((S)-SW228703) with blood and liver-stage antimalarial activity associated with the Cyclic Amine Resistance Locus (PfCARL)

L. S. Imlay, A. K. Lawong, S. Gahalawat, A. Kumar, C. Xing, N. Mittal, S. Wittlin, A. Churchyard, H. Niederstrasser, B. Crespo-Fernandez, B. Posner, F.-J. S. Gamo, J. Baum, E. Winzeler, B. Laleu, , M. A. Phillips

This paper identifies (S)-SW228703, a tyrosine amide with fast-killing antimalarial activity against blood and liver stages of Plasmodium falciparum, and links resistance to mutations in PfCARL and PfACT.

bioRxiv · Oct 16, 2022Microbiology

4D live-cell imaging of microgametogenesis in the human malaria parasite Plasmodium falciparum

S. Yahiya, S. Jordan, H. X. Smith, D. C. A. Gaboriau, M. T. Famodimu, F. A. Dahalan, A. Churchyard, G. W. Ashdown, J. Baum

This study uses 4D live-cell imaging to analyze microgametogenesis in Plasmodium falciparum, revealing proteasomal activity's critical role in DNA replication and axoneme formation.

bioRxiv · Jul 28, 2021Microbiology

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

L. E. de Vries, P. A. Jansen, C. Barcelo, J. Munro, J. M. Verhoef, C. F. A. Pasaje, K. Rubiano, J. Striepen, J. M. Bolscher, R. Henderson, T. Huijs, K. M. Koolen, P. K. Tumwebaze, T. Yeo, A. C. Aguiar, , K. J. Dechering

This paper characterizes MMV693183, a novel antimalarial compound targeting acetyl-CoA synthetase, showing in vitro and in vivo efficacy against Plasmodium species and transmission blocking.

bioRxiv · May 12, 2021Microbiology