Author

A. De Sciscio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Assay:metagenomics· 1

Frequent Co-Authors

E. Grant· 3 shared M. S. Desai· 3 shared A. Parrish· 2 shared M. Boudaud· 2 shared M. Wolter· 2 shared S. Willieme· 2 shared A. Campbell· 1 shared A. J. Macpherson· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMicrobiology

E. Grant

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Gut microbiome-based prediction of autoimmune neuroinflammation

A. Steimle, M. Neumann, E. Grant, S. Willieme, A. De Sciscio, A. Parrish, M. Ollert, E. Miyauchi, T. Soga, S. Fukuda, H. Ohno, M. S. Desai

The paper identifies a microbial risk factor for autoimmune neuroinflammation by analyzing microbiota compositions and host immune responses in a mouse model of multiple sclerosis.

bioRxiv · Apr 14, 2023 · PreprintMicrobiology

Opposing diet, microbiome and metabolite mechanisms regulate inflammatory bowel disease in a genetically susceptible host

G. Vasconcelos Pereira, M. Boudaud, M. Wolter, C. Alexander, A. De Sciscio, E. Grant, B. Caetano Trindade, S. Singh, A. Campbell, N. Pudlo, S. Willieme, S. Craig, K. Kim, T. Denike-Duval, L. Kennedy, , E. C. Martens

The paper shows that low dietary fiber promotes colitis in genetically susceptible mice by eroding mucus, while a fiber-free diet increases anti-inflammatory metabolites, highlighting microbial function over taxa in IBD regulation.

bioRxiv · Apr 3, 2022Microbiology

Mucin-degrading gut bacteria promote anti-parasitic immunity

M. Wolter, M. Boudaud, E. Grant, A. Parrish, A. De Sciscio, S. Thompson, J.-J. Gerardy, M. Mittelbronn, D. J. Thornton, A. J. Macpherson, R. K. Grencis, M. S. Desai

This study shows that mucin-degrading gut bacteria influence anti-parasitic immunity by modulating host immune responses, with dietary fiber affecting this interaction.

bioRxiv · Feb 28, 2022 · PreprintImmunology