Author

A. Dopazo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:scRNA-seq· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

A. Benguria· 3 shared E. Vazquez· 2 shared F. Sanchez-Cabo· 2 shared A. Benguria Filippini· 1 shared A. Efeyan· 1 shared A. Garcia-Jimenez· 1 shared A. Hernandez-Barranco· 1 shared A. Ortega-Molina· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersImmunology

A. Benguria

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Role of Lamin A/C on dendritic cell function in antiviral immunity

B. Herrero-Fernandez, R. Gomez-Bris, M. Ortega-Zapero, A. Saez, S. Iborra, V. Zorita, A. Quintas, E. Vazquez, A. Dopazo, F. Sanchez-Madrid, S. M. Arribas, J. M. Gonzalez-Granado

This study shows that lamin A/C is essential for dendritic cell function in antiviral immunity by modulating epigenetic and transcriptional processes.

bioRxiv · May 14, 2024Immunology

NGFR regulates germinal center B-cell activation and negative selection

A. Hernandez-Barranco, M. S. Mazariegos, V. Santos, E. Caleiras, L. Nogues, F. Mourcin, S. Leonard, C. Oblet, S. Genebrier, D. Rossille, A. Benguria, E. Vazquez, A. Dopazo, A. Efeyan, A. Ortega-Molina, , H. Peinado

This study shows that NGFR regulates germinal center B-cell activation and negative selection by maintaining GC structure and function, affecting antibody production and immune tolerance.

bioRxiv · Jul 14, 2023 · PreprintImmunology

Long-term cytotoxic NK cells with broad anti-tumour capacity proliferate selectively, without exhaustion, after BCG priming and extremely low doses of cytokines

M.-J. Felgueres, G. Esteso, A. Garcia-Jimenez, A. Dopazo, L. Martinez-Pineiro, H. T. Reyburn, M. Vales-Gomez

This paper describes a method to generate long-lived, cytotoxic NK cells with broad anti-tumour activity using BCG priming and low-dose cytokines, without cell sorting or exhaustion.

bioRxiv · Jun 7, 2023 · PreprintImmunology

Incongruence between transcriptional and vascular pathophysiological cell states

M. Fernandez-Chacon, S. Muhleder, A. Regano, L. Garcia-Ortega, C. Torroja, M. Lytvyn, M. S. Sanchez-Munoz, V. Casquero-Garcia, E. Camafeita, J. Vazquez, A. Benguria, A. Dopazo, F. Sanchez-Cabo, H. Carter, R. Benedito

This study compares the vascular phenotypes and transcriptional states of Notch pathway mutants, revealing discrepancies between molecular changes and vascular pathology.

bioRxiv · Apr 16, 2023Physiology

Antiviral State of CD1c+ cDC contributes to Increased Maturation and Activation of Cytotoxic Natural Killer cells in Sjogrens Syndrome

I. Sanchez Cerrillo, M. Calvet Mirabent, A. Triguero Martinez, D. Calzada Fraile, C. Delgado Alfaro, M. Valdivia, M. ramirez-Huesca, E. Vazquez de Luis, A. Benguria Filippini, R. Moreno Vellisca, M. M. Adrados, H. de la Fuente, I. Tsukalov, E. Roy Vallejo, A. Ramiro, , E. Martin-Gayo

The paper identifies CD1c+ cDCs in pSS patients that enhance NK cell activation through antiviral IFN signatures and ligands for NK receptors, contributing to disease pathology.

bioRxiv · Mar 13, 2022 · PreprintImmunology

Single cell clonal analysis identifies an AID-dependent pathway of plasma cell differentiation

C. Gomez-Escolar, A. Serrano-Navarro, A. Benguria, A. Dopazo, F. Sanchez-Cabo, A. R. Ramiro

The paper identifies an AID-dependent pathway in GC B cell differentiation by analyzing single-cell transcriptomes and immunoglobulin clonal data in a mouse model.

bioRxiv · Jun 3, 2021Immunology