Author

A. E. Williams

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

L. M. Arendt· 2 shared A. D'Alessandro· 1 shared A. Davis· 1 shared A. de Silva Orfano· 1 shared A. Gandhi· 1 shared A. Janquart· 1 shared A. Liou· 1 shared A. P. Havas· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

L. M. Arendt

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Author profile →

5 papers

Recent·Most cited

Age-associated repression of HNF4α is a driver and potential therapeutic target in liver metabolic dysfunction

Jessica Proulx, K. A. Lande, X. Lei, A. P. Havas, M. Garcia Teneche, A. Rajesh, H. Tanaka, M. A. LaPorta, G. Evensen, S. Mamde, L. Wang, A. Gandhi, R. Arnold, A. Davis, A. Liou, , P. D. Adams

This study identifies age-associated repression of HNF4α as a driver of liver metabolic dysfunction and shows that restoring HNF4α can reverse some age-related liver defects.

bioRxiv · Nov 9, 2026 · PreprintMolecular Biology

Alterations in the Mammary Gland and Tumor Microenvironment of Formerly Obese Mice

G. Kuziel, B. N. Moore, G. P. Haugstad, Y. Xiong, A. E. Williams, L. M. Arendt

This study shows that weight loss in formerly obese mice reduces mammary gland inflammation and fibrosis but does not fully resolve collagen deposition in tumors, suggesting partial microenvironmental recovery.

bioRxiv · Jun 14, 2023Cancer Biology

Age-dependent roles of cardiac remodeling in sepsis defense and pathogenesis

K. K. Sanchez, J. L. McCarville, S. J. Stengel, J. M. Snyder, A. E. Williams, J. S. Ayres

This study shows that age affects disease tolerance mechanisms in sepsis, with a cardioprotective pathway in young mice causing heart damage in older mice.

bioRxiv · Mar 14, 2023 · PreprintImmunology

Paratransgenic manipulation of tsetse miR275 alters the physiological homeostasis of the flys midgut environment

L. Yang, B. Weiss, A. E. Williams, E. Aksoy, A. de Silva Orfano, J. H. Son, Y. Wu, A. Vigneron, M. Karakus, S. Aksoy

This study uses paratransgenesis to knock down miR275 in tsetse flies, showing it disrupts midgut physiology and trypanosome infection.

bioRxiv · Mar 15, 2021Microbiology

Obesity-Activated Lung Stomal Cells Promote Myeloid-Lineage Cell Accumulation and Breast Cancer Metastasis

L. E. Hillers-Ziemer, A. E. Williams, A. Janquart, C. Grogan, V. Thompson, A. Sanchez, L. M. Arendt

This study shows obesity modifies lung stromal cells to create pre-metastatic niches that enhance myeloid cell recruitment and breast cancer metastasis.

bioRxiv · Nov 23, 2020Cancer Biology