Author

S. K. Varanasi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

B. Mcdonald· 3 shared D. Chen· 3 shared S. M. Kaech· 3 shared V. Tripple· 3 shared A. Williams· 2 shared E. Casillas· 2 shared H. K. Chung· 2 shared Q. Yang· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

B. Mcdonald

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Atlas-Guided Discovery of Transcription Factors for T Cell Programming

H. K. Chung, C. Liu, A. Battu, A. N. Jambor, B. M. Pratt, F. Xie, B. P. Riesenberg, E. Casillas, M. Sun, E. Landoni, Y. Li, Q. Ye, D. Joo, J. Green, Z. Syed, , S. M. Kaech

The paper identifies transcription factors driving distinct CD8+ T cell states and shows their impact on tumor control and immunotherapy.

bioRxiv · Jan 3, 2023Immunology

CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection

S. E. Redford, S. K. Varanasi, K. K. Sanchez, J. S. Ayres

This study identifies CD4+ T cells as regulators of sickness-induced anorexia and fat wasting during a chronic parasitic infection, revealing a decoupling between immune resistance and cachexia.

bioRxiv · Dec 17, 2022Immunology

A microglia-CD4+ T cell partnership generates protective anti-tumor immunity to glioblastoma

D. Chen, S. K. Varanasi, T. Hara, K. Traina, B. McDonald, Y. Farsakoglu, J. Clanton, S. Xu, T. H. Mann, V. Du, H. K. Chung, Z. Xu, V. Tripple, E. Casillas, S. Ma, , S. M. Kaech

This study identifies a microglia-CD4+ T cell interaction that enhances anti-glioblastoma immunity through IFN-gamma-mediated tumor surveillance and phagocytosis.

bioRxiv · Aug 12, 2022 · PreprintImmunology

Oxidized Lipids and CD36-Mediated Lipid Peroxidation in CD8 T Cells Suppress Anti-Tumor Immune Responses

S. Xu, O. Chaudhary, P. Rodriguez-Morales, X. Sun, R. Zappasodi, Z. Xu, A. F. M. Pinto, A. Williams, D. Chen, J. S. Low, Y. Farsakoglu, W. Tang, H. Wang, S. K. Varanasi, B. McDonald, , S. M. Kaech

This study identifies CD36-mediated lipid peroxidation driven by oxidized lipids as a mechanism suppressing anti-tumor CD8 T cell functions in murine tumors.

bioRxiv · Sep 3, 2020Immunology