Author

A. F. Thompson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

J. Stumpff· 2 shared A. Alfieri· 1 shared A. Wandinger-Ness· 1 shared B.-S. Herbert· 1 shared C. D. Wells· 1 shared C. Sindelar· 1 shared D. Babovic-Vuksanovic· 1 shared E. W. Klee· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

J. Stumpff

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Reconstitution of renal cyst formation in 3D culture reveals a role for AMOT and Yap1 in determining cyst size.

C. D. Wells, K. Lange, A. F. Thompson, W. M. Xu, S. G. Clendenon, J. S. Underwood, P. Harris, B.-S. Herbert, J. A. Glazier, A. Wandinger-Ness, R. L. Bacallao

The paper shows that Cadherin 8 and YAP1 drive cyst initiation and expansion, respectively, in 3D kidney cultures, with AMOTL1 inhibiting expansion.

bioRxiv · Mar 1, 2022 · PreprintCell Biology

Pathogenic mutations in the chromokinesin KIF22 disrupt anaphase chromosome segregation

A. F. Thompson, P. R. Blackburn, N. S. Arons, S. N. Stevens, D. Babovic-Vuksanovic, J. B. Lian, E. W. Klee, J. Stumpff

This study shows that pathogenic KIF22 mutations disrupt anaphase chromosome segregation, leading to cell proliferation issues and cytokinesis failure.

bioRxiv · Sep 29, 2021 · PreprintCell Biology

The Kinesin-5 Tail Domain Directly Modulates the Mechanochemical Cycle of the Motor for Anti-Parallel Microtubule Sliding

T. Bodrug, E. Wilson-Kubalek, S. Nithianantham, A. F. Thompson, A. Alfieri, I. Gaska, J. Major, G. Debs, S. Inagaki, P. Gutierrez, L. Gheber, R. McKenney, C. Sindelar, R. Milligan, J. Stumpff, , J. Al-Bassam

This study shows the kinesin-5 tail domain regulates motor activity by modulating ATP hydrolysis and microtubule sliding, leading to slow motility and force generation.

bioRxiv · Aug 8, 2019Biophysics