An Essential Role of UBXN3B in B Lymphopoiesis
T. Geng, D. Yang, T. Lin, A. G. Harrison, B. Wang, B. Torrance, K. Wang, Y. Wang, L. Yang, L. Haynes, G. Cheng, A. T. Vella, E. Fikrig, P. WANG
This study identifies UBXN3B's critical role in B lymphopoiesis by maintaining BLNK stability and pre-BCR signaling, leading to impaired B cell development and increased vulnerability to viral infections.
bioRxiv · Mar 4, 2021 · PreprintImmunology