A. G. Smith

Automated Seminal Root Angle Measurement with Corrective Annotation

The paper introduces an automated method for measuring seminal root angles from images and validates its accuracy against manual measurements.

New Interactive Machine Learning Tool for Marine Image Analysis

This paper introduces RootPainter, an interactive machine learning tool for marine image analysis, demonstrating its accuracy and efficiency in measuring sponges in underwater images.

Light management by algal aggregates in living photosynthetic hydrogels.

This study investigates how algal aggregates in hydrogels improve light distribution and biomass growth by reducing photoinhibition and increasing light penetration.

Presence of vitamin B12 metabolism in the last common ancestor of land plants

The paper identifies B12 metabolism in the last common ancestor of land plants through phylogenetic analysis of genes across plant and algal genomes.

The conserved protein CBA1 is required for vitamin B12 uptake in different algal lineages

Knockout mutants and physiological studies show CBA1 is essential for vitamin B12 uptake in Chlamydomonas reinhardtii and Phaeodactylum tricornutum.

Overexpression of PSR1 in Chlamydomonas reinhardtii induces luxury phosphorus uptake

Overexpressing PSR1 in Chlamydomonas reinhardtii increases phosphorus uptake and PolyP granule size, enabling efficient Pi removal from wastewater.

Exploring the onset of B12-based mutualisms using a recently evolved Chlamydomonas auxotroph and B12-producing bacteria

The paper investigates how a B12-dependent alga forms mutualisms with B12-producing bacteria, finding that higher B12 release by bacteria benefits both partners in co-culture.

Dynamics of deep water and N uptake under varied N and water supply

This study evaluates how reduced nitrogen and water supply affects deep nitrogen and water uptake in winter oilseed rape, finding that nitrogen supply primarily influences deep nitrogen uptake efficiency.

Synthetic algal-bacteria consortia for space-efficient microalgal growth in a simple hydrogel system

This study develops a hydrogel system with algal-bacterial consortia that enhances microalgal growth rates by 3-fold compared to algae alone.

Digging roots is easier with AI

This study demonstrates that using CNN-based software like RootPainter can significantly reduce time and effort in root quantification by accurately analyzing root images with and without debris.

Recapitulation of HIV-1 Env-Antibody Coevolution in Macaques Leading to Neutralization Breadth

Virus-antibody coevolution in rhesus macaques recapitulates developmental features of human antibodies.

Phenotypic melanoma heterogeneity is regulated through cell-matrix interaction-dependent changes in tumor microarchitecture

This paper shows that melanoma phenotypic heterogeneity is controlled by cell-ECM crosstalk, altering tumor microarchitecture and mechanotransduction.

RootPainter: Deep Learning Segmentation of Biological Images with Corrective Annotation

RootPainter is a software tool for training deep neural networks in biological image analysis, tested on plant root datasets for segmentation tasks.

Combining SIMS and mechanistic modelling to reveal nutrient kinetics in an algal-bacterial mutualism

The paper combines SIMS with mechanistic modeling to study nutrient kinetics in a synthetic algal-bacterial mutualism, revealing delays in cross-feeding due to initial carbon pools.

Physiological and molecular responses of a newly evolved auxotroph of Chlamydomonas to B12 deprivation

This study examines the physiological and molecular responses of a newly evolved B12-dependent mutant of Chlamydomonas to B12 deprivation and shows that co-culturing with B12-producing bacteria improves survival and B12 use-efficiency.

Bionic 3D printed corals

This study develops 3D printed bionic corals that support high-density microalgal growth, mimicking coral structure and function to enhance photosynthesis and bioproduct generation.

Mutualism between microbial populations in structured environments: the role of geometry in diffusive exchanges

The paper models how geometric structure affects diffusive exchanges in microbial mutualisms, showing counterintuitive dependencies on diffusion geometry in a synthetic algal-bacterial co-culture.