Author

G. M. Boyle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H. Schaider· 2 shared A. G. Smith· 1 shared A. M. Kane· 1 shared B. A. Leggett· 1 shared B. Gabrielli· 1 shared B. Salik· 1 shared C. A. Tonnessen-Murray· 1 shared C. E. Bond· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

H. Schaider

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Aspirin synergizes with regorafenib to reduce growth of colorectal cancer

C. Su, L. J. Fennell, C. E. Bond, A. M. Kane, G. Kerr, T. Jarde, D. Micati, R. M. Engel, W. H. Chan, S. Hlavca, S. Archer, P. J. McMurrick, H. Hammerlindl, F. Lim, B. Salik, , V. L. Whitehall

This study shows that aspirin and regorafenib together reduce colorectal cancer growth in preclinical models by inhibiting the PI3K-Akt-mTOR pathway and activating AMPK.

bioRxiv · Feb 11, 2022 · PreprintCancer Biology

Phenotypic melanoma heterogeneity is regulated through cell-matrix interaction-dependent changes in tumor microarchitecture

L. Spoerri, C. A. Tonnessen-Murray, G. Gunasingh, D. S. Hill, K. A. Beaumont, R. J. Jurek, J. Chauhan, G. C. Vanwalleghem, M. E. Fane, S. M. Daignault-Mill, N. Matigian, G. M. Boyle, E. K. Scott, A. G. Smith, S. J. Stehbens, , N. K. Haass

This paper shows that melanoma phenotypic heterogeneity is controlled by cell-ECM crosstalk, altering tumor microarchitecture and mechanotransduction.

bioRxiv · Jun 9, 2020 · PreprintCancer Biology

Kunitz type protease inhibitor EgKI-1 from the canine tapeworm Echinococcus granulosus as a promising anti-cancer therapeutic

S. L. Ranasinghe, G. M. Boyle, K. Fischer, J. Potriquet, J. P. Mulvenna, D. P. McManus

This study identifies EgKI-1, a protease inhibitor from Echinococcus granulosus, as a potential anti-cancer agent that inhibits cancer cell growth and migration in vitro and reduces tumor growth in vivo.

bioRxiv · Jun 27, 2018Cancer Biology