Author

A. Goncalves da Silva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 4 Approach:experimental assay· 3 Organism:human· 3 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:variant calling· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

B. P. Howden· 4 shared T. P. Stinear· 4 shared T. Seemann· 4 shared G. P. Carter· 3 shared I. R. Monk· 2 shared M. B. Schultz· 2 shared R. Guerillot· 2 shared S. A. Ballard· 2 shared

Activity by Year

2016-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersMicrobiology

B. P. Howden

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Author profile →

5 papers

Recent·Most cited

Bridging the gap between bioinformatics and the clinical and public health microbiology laboratory: An ISO-accredited genomics workflow for antimicrobial resistance

N. L. Sherry, K. Horan, S. A. Ballard, A. Goncalves da Silva, C. L. Gorrie, M. B. Schultz, K. Stevens, M. Valcanis, M. Sait, T. P. Stinear, B. P. Howden, T. Seemann

This paper develops and validates abritAMR, an ISO-accredited bioinformatics platform for detecting antimicrobial resistance genes with high accuracy and specificity.

bioRxiv · May 26, 2022 · PreprintMicrobiology

Functional genomics reveals extensive diversity in Staphylococcus epidermidis restriction modification systems compared to Staphylococcus aureus.

J. Y. Lee, G. P. Carter, S. J. Pidot, R. Guerillot, T. Seeman, A. Goncalves da Silva, T. J. Foster, B. P. Howden, T. P. Stinear, I. R. Monk

The paper identifies extensive diversity in type I restriction modification systems in Staphylococcus epidermidis compared to Staphylococcus aureus, enabling efficient genetic manipulation of clinically relevant strains.

bioRxiv · May 22, 2019 · PreprintMicrobiology

Remodelling of pSK1 Family Plasmids and Enhanced Chlorhexidine Tolerance in Methicillin-Resistant Staphylococcus aureus

S. L. Baines, S. O. Jensen, N. Firth, A. Goncalves da Silva, T. Seemann, G. P. Carter, D. A. Williamson, B. P. Howden, T. P. Stinear

This study examines the evolution of pSK1 family plasmids in MRSA ST239 isolates over 32 years, showing their role in enhancing chlorhexidine tolerance and gentamicin resistance.

bioRxiv · Oct 31, 2018Evolutionary Biology

A Supervised Statistical Learning Approach For Accurate Legionella pneumophila Source Attribution During Outbreaks

A. Buultjens, K. Chua, S. Baines, J. Kwong, W. Gao, Z. Cutcher, S. Adcock, S. Ballard, M. B. Schultz, T. Tomita, N. Subasinghe, G. Carter, S. Pidot, L. Franklin, T. Seemann, , T. Stinear

This paper develops a statistical learning method to accurately attribute Legionella pneumophila outbreaks by analyzing genomic data and comparing it to epidemiological data.

bioRxiv · Aug 11, 2017Microbiology

Increasing tolerance of hospital Enterococcus faecium to hand-wash alcohols

S. J. Pidot, W. Gao, A. H. Buultjens, I. R. Monk, R. Guerillot, G. P. Carter, J. Y. H. Lee, M. M. C. Lam, S. A. Ballard, M. L. Grayson, A. A. Mahony, E. A. Grabsch, D. Kotsanas, T. Korman, G. W. Coombs, , T. P. Stinear

The paper shows hospital Enterococcus faecium isolates from 2010 onward are 10-fold more tolerant to alcohol-based disinfectants than older isolates, leading to increased gastrointestinal colonization in mice.

bioRxiv · May 16, 2016Microbiology