Author

A. Groisman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Organism:C. elegans· 1 Research Focus:cell-cell communication· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

E. Gutierrez· 3 shared A. Mogilner· 2 shared A. Bachir· 1 shared A. Desai· 1 shared A. J. Whitewood· 1 shared A. R. Horwitz· 1 shared B. T. Goult· 1 shared C. A. Wilson· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersCell Biology

E. Gutierrez

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Talin-vinculin precomplex drives adhesion maturation by accelerated force transmission and vinculin recruitment

S. J. Han, E. V. Azarova, A. J. Whitewood, A. Bachir, E. Guttierrez, A. Groisman, A. R. Horwitz, B. T. Goult, K. Dean, G. Danuser

The paper shows that talin's precomplex with vinculin accelerates adhesion maturation by enhancing vinculin recruitment and force transmission.

bioRxiv · Jan 4, 2021 · PreprintCell Biology

Modeling cell turning by mechanics at the cell rear

K.-C. Lee, G. Allen, E. Barnhart, M. Tsuchida, C. Wilson, E. Gutierrez, A. Groisman, J. Theriot, A. Mogilner

The paper models cell turning by incorporating mechanosensitive adhesions into a mechanical model of keratocyte motility, showing how this affects cell behavior compared to uniform adhesion.

bioRxiv · Jun 3, 2020 · PreprintBiophysics

Cell Mechanics at the Rear Act To Steer the Direction of Cell Migration

G. M. Allen, K. C. Lee, E. L. Barnhart, M. A. Tsuchida, C. A. Wilson, E. Gutierrez, A. Groisman, A. Mogilner, J. A. Theriot

The paper investigates how mechanical asymmetries at the rear of fish keratocytes drive cell turning, showing that actin flow and myosin II contractility, rather than leading edge protrusion, are key to steering migration.

bioRxiv · Oct 15, 2018Cell Biology

CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytia

K.-Y. Lee, R. A. Green, E. Gutierrez, J. S. Gomez-Cavazos, I. Kolotuev, S. Wang, A. Desai, A. Groisman, K. Oegema

This study shows CYK-4, but not ZEN-4, is required for oocyte cellularization in C. elegans germline syncytia through a C1-GAP module that targets it to intercellular bridges.

bioRxiv · Sep 29, 2017Cell Biology