Author

A. J. Afzal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. A. Shibl· 1 shared A. D. Hamilton· 1 shared A. Isaac· 1 shared A. R. Mohamed· 1 shared D. Maity· 1 shared G. Esposito· 1 shared G. Skrzypek· 1 shared I. Chehade· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperEcology

A. A. Shibl

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Molecular mechanisms of microbiome modulation by the eukaryotic secondary metabolite azelaic acid

A. A. Shibl, M. A. Ochsenkuhn, A. R. Mohamed, A. Isaac, L. S. Y. Coe, Y. Yun, G. Skrzypek, J.-B. Raina, J. R. Seymour, A. J. Afzal, S. A. Amin

This study investigates how azelaic acid affects two microalgal-associated bacteria, identifying uptake mechanisms and toxicity pathways, and shows its role in shaping microbial communities in marine environments.

bioRxiv · Apr 8, 2022Ecology

Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function

L. Palanikumar, L. Karpauskaite, S. Hassan, M. Alam, M. Al-Sayegh, I. Chehade, D. Maity, L. Ali, Z. Falls, R. Samudrala, M. Kalmouni, Y. Hunashal, J. Ahmed, S. Karapetyan, R. Pasricha, , M. Magzoub

This study identifies a small-molecule amyloid inhibitor that disrupts mutant p53 aggregation, restores its function, and reduces tumor growth in xenograft models.

bioRxiv · Aug 10, 2020Cancer Biology