Author

L. Ali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

L. Palanikumar· 2 shared M. Kalmouni· 2 shared M. Magzoub· 2 shared R. Pasricha· 2 shared A. Afzal· 1 shared A. D. Hamilton· 1 shared A. J. Afzal· 1 shared A. Karlsson· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBioengineering

L. Palanikumar

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A benzoxazolylurea inhibits VraS and enhances antimicrobials against vancomycin intermediate-resistant Staphylococcus aureus

A. Sarkar, M. H. Abdelaziz, E. P. Heckler, L. Ali, B. Cagle-White, S. Bhattarai, N. Smith, R. A. Coover

bioRxiv · Aug 31, 2023 · PreprintPharmacology & Toxicology

pH-responsive upconversion mesoporous silica nanospheres for combined multimodal diagnostic imaging and targeted photodynamic and photothermal cancer therapy

L. Palanikumar, M. Kalmouni, T. Houhou, O. Abdullah, L. Ali, R. Pasricha, S. Thomas, A. Afzal, F. N. Barrera, M. Magzoub

This paper develops ATRAM-functionalized upconversion mesoporous silica nanospheres for multimodal imaging and combined photodynamic/photothermal cancer therapy, showing effective tumor targeting and treatment with minimal toxicity.

bioRxiv · May 22, 2023 · PreprintBioengineering

Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function

L. Palanikumar, L. Karpauskaite, S. Hassan, M. Alam, M. Al-Sayegh, I. Chehade, D. Maity, L. Ali, Z. Falls, R. Samudrala, M. Kalmouni, Y. Hunashal, J. Ahmed, S. Karapetyan, R. Pasricha, , M. Magzoub

This study identifies a small-molecule amyloid inhibitor that disrupts mutant p53 aggregation, restores its function, and reduces tumor growth in xenograft models.

bioRxiv · Aug 10, 2020Cancer Biology

Core-2 O-glycans are required for Galectin-3 interaction with the osteoarthritis related protein lubricin

S. A. Flowers, K. A. Thomsson, L. Ali, S. Huang, Y. Mthembu, S. C. Regmi, J. Holgersson, T. A. Schimdt, O. Rolfson, L. I. Bjorkman, M. Sundqvist, A. Karlsson, G. D. Jay, T. Eisler, R. Krawetz, N. G. Karlsson

The paper shows that core-2 O-glycans are necessary for galectin-3 to bind lubricin, and this interaction is reduced in late-stage osteoarthritis.

bioRxiv · Dec 20, 2019Biochemistry