Author

J. Ahmed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cancer Biology· 1 Plant Biology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Organism:Arabidopsis· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

S. Kumar· 3 shared C. M. Donnelly· 2 shared J. A. Joseph· 2 shared T. C. Fitch· 2 shared A. D. Hamilton· 1 shared A. G. Thomas· 1 shared A. J. Afzal· 1 shared A. Ledreux· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiochemistry

S. Kumar

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Menin regulates androgen receptor- and MLL-driven condensation, upsetting regulation of cellular AR-driven transcription.

J. Ahmed, J. K. Claridge, A. Meszaros, P. Tompa

This study shows menin regulates AR and MLL-driven RNA condensates through dimerization, affecting transcription regulation and contributing to cancer when disrupted.

bioRxiv · Aug 4, 2023 · PreprintBiochemistry

Interdependence of plasma membrane nanoscale dynamics of a kinase and its cognate substrate underlies Arabidopsis response to viral infection

M.-D. Jolivet, A.-F. Deroubaix, M. Boudsocq, N. B. Abel, M. Rocher, T. Robbe, V. Wattelet, J. Huard, D. Lefebvre, Y.-J. Lu, B. Day, G. Saias, J. Ahmed, V. Cotelle, N. Giovinazzo, , V. Germain

This study shows that CPK3 and its substrate REM1.2 interact dynamically at the plasma membrane, influencing viral propagation in Arabidopsis.

bioRxiv · Jul 31, 2023Plant Biology

Knowledge, attitudes and biosecurity practices among the small-scale dairy farmers in Sylhet District, Bangladesh

T. Chowdhury, J. Ahmed, M. T. Hossain, M. C. Roy, M. A.-U. Zaman, M. N. Uddin, M. M. Rahman, M. G. Kabir, F. M. A. Hossain

This study assesses knowledge, attitudes, and biosecurity practices among small-scale dairy farmers in Bangladesh and finds strong correlations between these factors and human health outcomes.

bioRxiv · May 28, 2023Scientific Communication & Education

A 2D Fragment-Assisted Protein Mimetic Approach to Rescue α-Synuclein Aggregation Mediated Early and Post-Disease Parkinsons Phenotypes

S. Kumar, N. H. Stillman, J. A. Joseph, J. Ahmed, R. A. Dohoney, T. D. Ball, A. G. Thomas, T. C. Fitch, C. M. Donnelly

This paper develops a 2D-FAST method to identify antagonists of α-synuclein aggregation, showing efficacy in C. elegans models of Parkinson's disease.

bioRxiv · Jul 11, 2022 · PreprintBiochemistry

Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly

J. Ahmed, T. C. Fitch, C. M. Donnelly, J. A. Joseph, M. M. Bassil, A. Son, C. Zhang, A. Ledreux, S. Horowitz, Y. Qin, D. Paredes, S. Kumar

This study identifies and validates novel therapeutic targets for Parkinson's disease by analyzing α-Synuclein self-assembly using foldamers and multiple assays.

bioRxiv · May 8, 2021Biochemistry

Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function

L. Palanikumar, L. Karpauskaite, S. Hassan, M. Alam, M. Al-Sayegh, I. Chehade, D. Maity, L. Ali, Z. Falls, R. Samudrala, M. Kalmouni, Y. Hunashal, J. Ahmed, S. Karapetyan, R. Pasricha, , M. Magzoub

This study identifies a small-molecule amyloid inhibitor that disrupts mutant p53 aggregation, restores its function, and reduces tumor growth in xenograft models.

bioRxiv · Aug 10, 2020Cancer Biology