Author

Y. Hunashal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

G. Esposito· 2 shared A. D. Hamilton· 1 shared A. J. Afzal· 1 shared A. Leonchiks· 1 shared D. Maity· 1 shared F. Fogolari· 1 shared F. Piano· 1 shared I. Chehade· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

G. Esposito

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Author profile →

2 papers

Recent·Most cited

Assessing nanobody interaction with SARS-CoV-2 Nsp9

G. Esposito, Y. Hunashal, M. Percipalle, F. Fogolari, T. Venit, A. Leonchiks, K. C. Gunsalus, F. Piano, P. Percipalle

This study investigates the interaction between SARS-CoV-2 Nsp9 and nanobody 2NSP90 using NMR spectroscopy and molecular dynamics simulations, revealing stoichiometry and epitope details.

bioRxiv · Oct 20, 2023Biophysics

Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function

L. Palanikumar, L. Karpauskaite, S. Hassan, M. Alam, M. Al-Sayegh, I. Chehade, D. Maity, L. Ali, Z. Falls, R. Samudrala, M. Kalmouni, Y. Hunashal, J. Ahmed, S. Karapetyan, R. Pasricha, , M. Magzoub

This study identifies a small-molecule amyloid inhibitor that disrupts mutant p53 aggregation, restores its function, and reduces tumor growth in xenograft models.

bioRxiv · Aug 10, 2020Cancer Biology