Author

A. J. Genders

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Physiology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:metabolism & bioenergetics· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

D. J. Bishop· 4 shared J. Botella· 3 shared J. Kuang· 3 shared N. J. Saner· 3 shared M. J.-C. Lee· 2 shared S. D. Martin· 2 shared A. Garnham· 1 shared C. Granata· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersPhysiology

D. J. Bishop

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Author profile →

5 papers

Recent·Most cited

Amyloid beta 42 alters cardiac metabolism and impairs cardiac function in obesity

L. G. Hall, J. K. Czeczor, T. Connor, J. Botella, K. A. De Jong, M. C. Renton, A. J. Genders, K. Venardos, S. D. Martin, S. T. Bond, K. Aston-Mourney, K. F. Howlett, J. A. Campbell, G. R. Collier, K. R. Walder, , S. McGee

This study shows that amyloid beta 42 from adipose tissue impairs cardiac function in obesity by affecting mitochondrial metabolism, and that neutralizing A{beta} can prevent obesity-induced cardiac dysfunction.

bioRxiv · Oct 2, 2022 · PreprintPhysiology

Methodological considerations when assessing mitochondrial respiration and biomarkers for mitochondrial content in human skeletal muscle

J. Kuang, N. J. Saner, J. Botella, M. J.-C. Lee, C. Granata, Z. Wang, X. Yan, J. Li, A. J. Genders, D. J. Bishop

This paper evaluates the reliability and reproducibility of methods for measuring mitochondrial respiration and citrate synthase activity in human skeletal muscle, identifying technical and biological variability factors.

bioRxiv · Mar 25, 2021Physiology

Changes in insulin resistance do not occur in parallel with changes in mitochondrial content and function in male rats

A. J. Genders, J. Kuang, E. C. Marin, N. J. Saner, J. Botella, M. Jacques, G. K. McConell, V. A. Andrade-Souza, J. Chagolla, D. J. Bishop

This study examines whether changes in insulin resistance in male rats on a high-fat diet correlate with mitochondrial content and function, finding no consistent association.

bioRxiv · Jul 6, 2020 · PreprintPhysiology

Exercise mitigates sleep-loss-induced changes in glucose tolerance, mitochondrial function, sarcoplasmic protein synthesis, and circadian rhythms.

N. J. Saner, M. J.-C. Lee, J. Kuang, N. W. Pitchford, G. D. Roach, A. Garnham, A. J. Genders, T. Stokes, E. A. Schroder, K. A. Esser, S. M. Phillips, D. J. Bishop, J. D. Bartlett

This study shows that high-intensity interval exercise mitigates sleep loss-induced impairments in glucose tolerance, mitochondrial function, sarcoplasmic protein synthesis, and circadian rhythms.

bioRxiv · Jun 21, 2020Physiology

A physiological drop in pH decreases mitochondrial respiration, and AMPK and Akt signalling, in L6 myocytes

A. J. Genders, S. D. Martin, S. L. McGee, D. J. Bishop

This study examines how changes in pH and lactate levels affect mitochondrial function and signaling pathways in L6 myotubes.

bioRxiv · May 25, 2018Cell Biology