Author

J. A. Campbell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Ebens· 1 shared A. J. Genders· 1 shared A. R. French· 1 shared A. S. Krupnick· 1 shared A. Shirali· 1 shared C. A. Nelson· 1 shared D. H. Fremont· 1 shared D. Lippold· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperImmunology

A. Ebens

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Author profile →

3 papers

Recent·Most cited

DNA-targeting and cell-penetrating antibody-drug conjugate

A. Shirali, V. Dubljevic, F. Cao, R. N. Nishimura, A. Ebens, J. A. Campbell, J. E. Hansen

The paper develops a DNA-targeting antibody-drug conjugate that selectively kills BRCA2-deficient tumors while sparing DNA repair-proficient ones.

bioRxiv · Apr 12, 2023 · PreprintImmunology

Amyloid beta 42 alters cardiac metabolism and impairs cardiac function in obesity

L. G. Hall, J. K. Czeczor, T. Connor, J. Botella, K. A. De Jong, M. C. Renton, A. J. Genders, K. Venardos, S. D. Martin, S. T. Bond, K. Aston-Mourney, K. F. Howlett, J. A. Campbell, G. R. Collier, K. R. Walder, , S. McGee

This study shows that amyloid beta 42 from adipose tissue impairs cardiac function in obesity by affecting mitochondrial metabolism, and that neutralizing A{beta} can prevent obesity-induced cardiac dysfunction.

bioRxiv · Oct 2, 2022 · PreprintPhysiology

Structural basis of cowpox evasion of NKG2D immunosurveillance

E. Lazear, M. M. Sun, X. Wang, T. L. Geurs, C. A. Nelson, J. A. Campbell, D. Lippold, A. S. Krupnick, R. S. Davis, L. N. Carayannolpoulos, A. R. French, D. H. Fremont

This study identifies OMCP as a cowpox virus protein that directly binds NKG2D to evade immune detection, revealing structural insights into its high-affinity interaction and zoonotic potential.

bioRxiv · Oct 7, 2019 · PreprintImmunology