Author

J. Kuang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 5 Cancer Biology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 7 Assay:bulk RNA-seq· 5 Assay:proteomics· 5 Research Focus:differential expression· 4 Approach:experimental assay· 4 Approach:statistical model· 4 Approach:biophysical modeling· 2 Research Focus:cell type annotation· 2

Frequent Co-Authors

D. J. Bishop· 6 shared N. J. Saner· 4 shared A. J. Genders· 3 shared J. Botella· 3 shared M. J.-C. Lee· 3 shared A. Garnham· 2 shared C. Granata· 2 shared L. Zhu· 2 shared

Activity by Year

2017-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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6 shared papersPhysiology

D. J. Bishop

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Author profile →

9 papers

Recent·Most cited

CLIPB4 is a central node in the protease network that regulates humoral immunity in Anopheles gambiae mosquitoes

X. Zhang, S. Zhang, J. Kuang, K. A. Sellens, B. Morejon, S. A. Saab, E. M. Metto, M. Li, M. Osta, C. An, C. T. Culbertson, C. M. Scoglio, K. Michel

The paper identifies CLIPB4 as a central protease in the immune network of Anopheles gambiae, showing its role in melanization and antibacterial immunity through interactions with SRPN2.

bioRxiv · Jul 7, 2023 · PreprintImmunology

Circulating tumor DNA profiling approach based on in silico background elimination guides patient classification of multiple cancers

M. Li, S. Xie, T. Hou, T. Shao, J. Kuang, C. Lu, X. Liu, L. Zhu, L. Zhu

The paper introduces MaGIC, a ctDNA profiling method that improves cancer classification and chemosensitivity prediction by reducing background noise from cfDNA.

bioRxiv · Aug 4, 2022 · PreprintCancer Biology

Methodological considerations when assessing mitochondrial respiration and biomarkers for mitochondrial content in human skeletal muscle

J. Kuang, N. J. Saner, J. Botella, M. J.-C. Lee, C. Granata, Z. Wang, X. Yan, J. Li, A. J. Genders, D. J. Bishop

This paper evaluates the reliability and reproducibility of methods for measuring mitochondrial respiration and citrate synthase activity in human skeletal muscle, identifying technical and biological variability factors.

bioRxiv · Mar 25, 2021Physiology

Training-induced bioenergetic improvement in human skeletal muscle is associated with non-stoichiometric changes in the mitochondrial proteome without reorganization of respiratory chain content

C. Granata, N. J. Caruana, J. Botella, N. A. Jamnick, K. Huynh, J. Kuang, H. A. Janssen, B. Reljic, N. A. Mellett, A. Laskowski, T. L. Stait, A. E. Frazier, M. T. Coughlan, P. J. Meikle, D. R. Thorburn, , D. J. Bishop

The paper investigates training-induced mitochondrial adaptations in human skeletal muscle, finding non-stoichiometric changes in the proteome and challenging previous assumptions about bioenergetic improvements.

bioRxiv · Feb 19, 2021Cell Biology

Comprehensive analysis of hsa-miR-654-5p's tumor-suppressing functions

C. Liu, L. Min, J. Kuang, C.-s. Zhu, J. Ma, X.-y. Qiu, X. Wu, T. Zhang, S. Xie, L. Zhu

This study investigates the tumor-suppressing functions of hsa-miR-654-5p in lung cancer through bioinformatic analysis and in vitro experiments, revealing its role in inhibiting EMT, proliferation, and migration.

bioRxiv · Dec 20, 2020Cancer Biology

Interpretation of exercise-induced changes in human skeletal muscle mRNA expression depends on the timing of the post-exercise biopsies

J. Kuang, C. McGinley, M. J.-C. Lee, N. J. Saner, A. Garnham, D. J. Bishop

This study shows that the timing of post-exercise muscle biopsies significantly affects the observed mRNA expression changes, emphasizing the need for comprehensive time-course analysis in exercise research.

bioRxiv · Aug 5, 2020Physiology

Changes in insulin resistance do not occur in parallel with changes in mitochondrial content and function in male rats

A. J. Genders, J. Kuang, E. C. Marin, N. J. Saner, J. Botella, M. Jacques, G. K. McConell, V. A. Andrade-Souza, J. Chagolla, D. J. Bishop

This study examines whether changes in insulin resistance in male rats on a high-fat diet correlate with mitochondrial content and function, finding no consistent association.

bioRxiv · Jul 6, 2020 · PreprintPhysiology

Exercise mitigates sleep-loss-induced changes in glucose tolerance, mitochondrial function, sarcoplasmic protein synthesis, and circadian rhythms.

N. J. Saner, M. J.-C. Lee, J. Kuang, N. W. Pitchford, G. D. Roach, A. Garnham, A. J. Genders, T. Stokes, E. A. Schroder, K. A. Esser, S. M. Phillips, D. J. Bishop, J. D. Bartlett

This study shows that high-intensity interval exercise mitigates sleep loss-induced impairments in glucose tolerance, mitochondrial function, sarcoplasmic protein synthesis, and circadian rhythms.

bioRxiv · Jun 21, 2020Physiology

Post-exercise cold-water immersion increases Na+,K+-ATPase α2-isoform mRNA content in parallel with elevated Sp1 expression in human skeletal muscle

D. Christiansen, R. M. Murphy, J. R. Broatch, J. Bangsbo, M. J. McKenna, J. Kuang, D. J. Bishop

This study shows sprint-interval exercise increases NKA1 and β3 mRNA while decreasing β2 mRNA in human skeletal muscle, and post-exercise cold-water immersion increases NKA2 mRNA alongside Sp1 expression.

bioRxiv · Jun 16, 2017Physiology