Author

A. J. Kwiatkowski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

B. G. Keselowsky· 2 shared D. Avram· 2 shared E. Y. Helm· 2 shared A. Restuccia· 1 shared A. Wanchoo· 1 shared B. D. Partain· 1 shared B. R. Kimmel· 1 shared C. L. Duvall· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioengineering

B. G. Keselowsky

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

STING-Activating Polymer-Drug Conjugates for Cancer Immunotherapy

T. L. Sheehy, A. J. Kwiatkowski, K. Arora, B. R. Kimmel, J. A. Schulman, K. Gibson-Corley, J. T. Wilson

This paper develops SAPCon, a polymer-drug conjugate that activates the STING pathway in tumors, enhancing immunotherapy efficacy by promoting an immunogenic microenvironment and improving tumor growth inhibition.

bioRxiv · Mar 23, 2024Bioengineering

Treatment with an Antigen-Specific Dual Microparticle System Reverses Advanced Multiple Sclerosis in Mice

A. J. Kwiatkowski, E. Y. Helm, J. M. Stewart, T. T. Drashansky, J. J. Cho, D. Avram, B. G. Keselowsky

This paper demonstrates that an antigen-specific dual microparticle treatment reverses hind limb paralysis in advanced EAE mice by reducing antigen presentation in APCs.

bioRxiv · Mar 25, 2022Bioengineering

Galectin-anchored indoleamine 2,3-dioxygenase suppresses local inflammation

E. Bracho-Sanchez, F. Rocha, S. K. Bedingfield, B. D. Partain, M. A. Brusko, J. M. Colazo, M. M. Fettis, S. A. Farhadi, E. Y. Helm, K. Koenders, A. J. Kwiatkowski, S. L. Macias, A. Restuccia, A. Wanchoo, D. Avram, , B. G. Keselowsky

This paper develops a fusion protein IDO-Gal3 that anchors immunosuppressive enzymes to tissues, effectively suppressing local inflammation in multiple disease models.

bioRxiv · May 7, 2021 · PreprintBioengineering