Submandibular Injection of Indoleamine 2,3-Dioxygenase Galectin-3 Fusion Protein Inhibits and Prevents Periodontal Disease Progression Over 12 Weeks
F. Rocha, C. Graves, A. Altitinchi, S. A. Farhadi, S. L. Macias, A. Wanchoo, G. A. Hudalla, B. G. Keselowsky, S. M. Wallet
This study shows that submandibular injection of IDO-Gal3 fusion protein prevents and halts periodontal disease progression by modulating immune responses and reducing bone loss.
bioRxiv · Jul 28, 2021 · PreprintImmunology