Author

B. G. Keselowsky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

G. A. Hudalla· 3 shared S. A. Farhadi· 3 shared A. J. Kwiatkowski· 2 shared A. Wanchoo· 2 shared B. D. Partain· 2 shared D. Avram· 2 shared E. Bracho-Sanchez· 2 shared E. Y. Helm· 2 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioengineering

G. A. Hudalla

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Treatment with an Antigen-Specific Dual Microparticle System Reverses Advanced Multiple Sclerosis in Mice

A. J. Kwiatkowski, E. Y. Helm, J. M. Stewart, T. T. Drashansky, J. J. Cho, D. Avram, B. G. Keselowsky

This paper demonstrates that an antigen-specific dual microparticle treatment reverses hind limb paralysis in advanced EAE mice by reducing antigen presentation in APCs.

bioRxiv · Mar 25, 2022Bioengineering

Submandibular Injection of Indoleamine 2,3-Dioxygenase Galectin-3 Fusion Protein Inhibits and Prevents Periodontal Disease Progression Over 12 Weeks

F. Rocha, C. Graves, A. Altitinchi, S. A. Farhadi, S. L. Macias, A. Wanchoo, G. A. Hudalla, B. G. Keselowsky, S. M. Wallet

This study shows that submandibular injection of IDO-Gal3 fusion protein prevents and halts periodontal disease progression by modulating immune responses and reducing bone loss.

bioRxiv · Jul 28, 2021 · PreprintImmunology

Intra-Articular Delivery of an Indoleamine 2,3-Dioxygenase Galectin-3 Fusion Protein for Osteoarthritis Treatment in Male Lewis Rats

B. D. Partain, E. Bracho-Sanchez, S. A. Farhadi, E. G. Yarmola, B. G. Keselowsky, G. A. Hudalla, K. D. Allen

This study evaluates an IDO-Gal3 fusion protein for treating osteoarthritis in rats, showing reduced inflammation and improved pain behaviors.

bioRxiv · Jul 21, 2021Bioengineering

Galectin-anchored indoleamine 2,3-dioxygenase suppresses local inflammation

E. Bracho-Sanchez, F. Rocha, S. K. Bedingfield, B. D. Partain, M. A. Brusko, J. M. Colazo, M. M. Fettis, S. A. Farhadi, E. Y. Helm, K. Koenders, A. J. Kwiatkowski, S. L. Macias, A. Restuccia, A. Wanchoo, D. Avram, , B. G. Keselowsky

This paper develops a fusion protein IDO-Gal3 that anchors immunosuppressive enzymes to tissues, effectively suppressing local inflammation in multiple disease models.

bioRxiv · May 7, 2021 · PreprintBioengineering