Author

A. J. Sharon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

L. C. Osborne· 2 shared R. L. Simister· 2 shared S. A. Crowe· 2 shared B. K. Hardman· 1 shared D. L. Gibson· 1 shared E. J. Wang· 1 shared H. A. Filyk· 1 shared H. G. Robinson· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

L. C. Osborne

Mutual co-authors in cluster

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2 papers

Recent·Most cited

The dietary fiber guar gum ameliorates experimental autoimmune encephalomyelitis via attenuated Th1 activation and differentiation

N. M. Fettig, H. G. Robonson, J. R. Allanach, K. M. Davis, R. L. Simister, E. J. Wang, A. J. Sharon, Y. Jiayu, S. J. Popple, D. L. Gibson, S. A. Crowe, M. S. Horwitz, L. C. Osborne

This study shows that guar gum reduces neuroinflammation in EAE by inhibiting Th1 activation and differentiation in CD4+ T cells, independent of microbiota or short chain fatty acid changes.

bioRxiv · Aug 4, 2022Immunology

STAT1-dependent tolerance of intestinal viral infection

H. A. Filyk, A. J. Sharon, N. M. Fonseca, R. L. Simister, W. Yuen, B. K. Hardman, H. G. Robinson, J. H. Seo, J. Rocha-Pereira, I. Welch, J. Neyts, S. A. Crowe, L. C. Osborne

This study identifies STAT1 as a key regulator of intestinal tolerance to a commensal virus, showing it restricts viral replication and prevents tissue damage without requiring T cell responses.

bioRxiv · Feb 13, 2020 · PreprintImmunology