Author

J. H. Seo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

A. Armaos· 1 shared A. J. Sharon· 1 shared A. Sheikh· 1 shared A. Valencia· 1 shared B. K. Hardman· 1 shared B. Wiles· 1 shared C. E. Rocheleau· 1 shared C. Giambartolomei· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperCancer Biology

A. Armaos

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

The PENGUIN approach to reconstruct protein interactions at enhancer-promoter regions and its application to prostate cancer

A. Armaos, F. Serra, I. Nunez Carpintero, J. H. Seo, S. C. Baca, S. Gustincich, A. Valencia, M. L. Freedman, D. Cirillo, C. Giambartolomei, G. G. Tartaglia

PENGUIN reconstructs protein interactions at enhancer-promoter regions and identifies cancer-associated SNPs in prostate cancer cell lines.

bioRxiv · Oct 20, 2022Cancer Biology

The Rab GTPase activating protein TBC-2 regulates endosomal localization of DAF-16 FOXO and lifespan

I. Meras, L. Chotard, T. Liontis, Z. Ratemi, B. Wiles, J. H. Seo, J. M. Van Raamsdonk, C. E. Rocheleau

This study shows that TBC-2 regulates DAF-16 FOXO endosomal localization, which affects lifespan and metabolism in C. elegans.

bioRxiv · Jun 4, 2021Cell Biology

IL-7 is essential for accumulation of antigen-specific CD8 T cells and to generate clonotype-specific effector responses during airway influenza/A infection.

A. Sheikh, J. Jackson, H. B. Shim, C. Yau, J. H. Seo, N. Abraham

bioRxiv · Apr 21, 2021 · PreprintImmunology

Prime editing enables precise genome editing in mouse liver and retina

H. Jang, J. H. Shin, D. H. Jo, J. H. Seo, G. Yu, R. Gopalappa, S.-R. Cho, J. H. Kim, H. H. Kim

This study demonstrates that prime editing can correct disease-causing mutations in adult mouse liver and retina, with minimal off-target effects.

bioRxiv · Jan 8, 2021 · PreprintBioengineering

STAT1-dependent tolerance of intestinal viral infection

H. A. Filyk, A. J. Sharon, N. M. Fonseca, R. L. Simister, W. Yuen, B. K. Hardman, H. G. Robinson, J. H. Seo, J. Rocha-Pereira, I. Welch, J. Neyts, S. A. Crowe, L. C. Osborne

This study identifies STAT1 as a key regulator of intestinal tolerance to a commensal virus, showing it restricts viral replication and prevents tissue damage without requiring T cell responses.

bioRxiv · Feb 13, 2020 · PreprintImmunology

Pinealectomy increases thermogenesis and decreases lipogenesis

M. K. Kim, S. M. Lee, J. Jung, Y. J. Kim, K. C. Moon, J. H. Seo, E. Ha

This study shows that pinealectomy in rats increases thermogenesis in brown adipose tissue and decreases lipogenesis in white adipose tissue and the liver.

bioRxiv · Oct 21, 2019Biochemistry