Author

J. R. Schneider

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. C. Joerger· 1 shared A. J. Fought· 1 shared A. J. Watson· 1 shared A. M. Carias· 1 shared B. Goins· 1 shared B.-T. Berger· 1 shared C. S. Evans· 1 shared D. N. Thakkar· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBiochemistry

A. C. Joerger

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Development of potent dual BET/HDAC inhibitors via pharmacophore merging and structure-guided optimization

N. Bauer, D.-I. Balourdas, J. R. Schneider, X. Zhang, L. M. Berger, B.-T. Berger, N. A. Klopp, J. T. Siveke, S. Knapp, A. C. Joerger

This study develops potent dual BET/HDAC inhibitors through pharmacophore merging and structure-guided optimization, showing improved potency and efficacy in cancer cell models.

bioRxiv · Jul 18, 2023 · PreprintBiochemistry

O-GlcNAcylation regulates neurofilament-light assembly and function and is perturbed by Charcot-Marie-Tooth disease mutations

D. T. Huynh, J. Hu, J. R. Schneider, K. N. Tsolova, E. J. Soderblom, A. J. Watson, J.-T. A. Chi, C. S. Evans, M. Boyce

This study shows that O-GlcNAcylation regulates NF-L assembly and function, and CMT mutations disrupt this process, linking glycosylation defects to neurodegeneration.

bioRxiv · Feb 22, 2023Cell Biology

PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure

R. A. Taylor, S. Xiao, A. M. Carias, M. D. McRaven, D. N. Thakkar, M. Arainga, E. J. Allen, K. A. Rogers, S. C. Kumarapperuma, S. Gong, A. J. Fought, M. R. Anderson, Y. Thomas, J. R. Schneider, B. Goins, , T. J. Hope

The paper uses PET/CT and fluorescent microscopy to show dIgA increases HIV virion distribution and penetration in colorectal tissue and lymph nodes after exposure.

bioRxiv · Dec 23, 2020Cell Biology