Author

L. P. Jackson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 6 Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 6 Approach:experimental assay· 5 Organism:human· 4 Assay:proteomics· 4 Approach:biophysical modeling· 2 Assay:cryo-EM· 2 Research Focus:protein folding & dynamics· 2 Organism:yeast· 2

Frequent Co-Authors

B. Xie· 5 shared A. K. Kendall· 4 shared T. R. Graham· 4 shared P. Xu· 3 shared J. A. MacGurn· 2 shared N. S. Diab· 2 shared A. K. Davies· 1 shared A. Kendall· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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5 shared papersCell Biology

B. Xie

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Tepsin binds LC3B to promote ATG9A export and delivery at the cell periphery

N. S. Wallace, J. E. Gadbery, C. I. Cohen, A. K. Kendall, L. P. Jackson

This study identifies tepsin's role in binding LC3B to facilitate ATG9A export from the TGN and delivery to the cell periphery, impacting autophagosome biogenesis.

bioRxiv · Jul 18, 2023 · PreprintCell Biology

An interaction between betaprime-COP and the ArfGAP, Glo3, maintains post-Golgi cargo recycling

B. Xie, C. Guillem, C. Jung, A. K. Kendall, S. Date, J. T. Best, T. R. Graham, L. P. Jackson

This study identifies the interaction between betaprime-COP and Glo3, an ArfGAP, showing it is essential for post-Golgi cargo recycling in yeast.

bioRxiv · May 25, 2022Cell Biology

Improved mammalian retromer cryo-EM structures reveal a new assembly interface

A. Kendall, M. Chandra, B. Xie, W. Wan, L. P. Jackson

The paper improves mammalian retromer cryo-EM structures, revealing a new assembly interface between VPS26A and VPS35 N-termini.

bioRxiv · Mar 4, 2022Biochemistry

Ubiquitination drives COPI priming and Golgi SNARE localization

S. S. Date, P. Xu, N. L. Hepowit, N. S. Diab, J. Best, B. Xie, J. Du, E. R. Strieter, L. P. Jackson, J. A. MacGurn, T. R. Graham

The paper identifies ubiquitin recognition by COPI as essential for Golgi SNARE localization and stabilizing interactions between Arf, COPI, and SNAREs.

bioRxiv · Nov 29, 2021Cell Biology

De novo macrocyclic peptides for inhibiting, stabilising and probing the function of the Retromer endosomal trafficking complex

K.-E. Chen, Q. Guo, T. A. Hill, Y. Cui, A. K. Kendall, Z. Yang, R. J. Hall, M. Healy, J. Sacharz, S. J. Norwood, S. Fonseka, B. Xie, R. C. Reid, N. Leneva, R. G. Parton, , B. M. Collins

The paper develops macrocyclic peptides that inhibit, stabilize, and probe the Retromer complex's function, showing high affinity and specificity for different subunits.

bioRxiv · Dec 3, 2020 · PreprintBiochemistry

Mammalian retromer is an adaptable scaffold for cargo sorting from endosomes

A. K. Kendall, B. Xie, P. Xu, J. Wang, R. Burcham, M. N. Frazier, E. Binshtein, H. Wei, T. R. Graham, T. Nakagawa, L. P. Jackson

This study identifies adaptable retromer structures and their role in cargo sorting from endosomes to the TGN or plasma membrane in mammals.

bioRxiv · May 15, 2019Cell Biology

AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A

A. K. Davies, D. N. Itzhak, J. R. Edgar, T. L. Archuleta, J. Hirst, L. P. Jackson, M. S. Robinson, G. H. H. Borner

The paper identifies AP-4's role in ATG9A trafficking via RUSC2-mediated vesicle transport, linking AP-4 deficiency to autophagy dysregulation in multiple cell types.

bioRxiv · Jun 11, 2018Cell Biology

COPI Mediates Recycling Of An Exocytic SNARE From Endosomes By Recognition Of A Ubiquitin Sorting Signal

P. Xu, H. Hankins, C. Macdonald, S. J. Erlinger, M. Frazier, N. S. Diab, R. C. Piper, L. P. Jackson, J. A. MacGurn, T. R. Graham

This study shows COPI mediates recycling of the SNARE Snc1 from early endosomes to the Golgi via recognition of a polyubiquitin sorting signal.

bioRxiv · May 3, 2017Cell Biology