Author

A. M. D. Becker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

C. G. Figdor· 2 shared C. M. Le Gall· 2 shared M. Verdoes· 2 shared Y. Dolen· 2 shared A. Cammarata· 1 shared A. Cevirgel· 1 shared A. E. H. Bentlage· 1 shared A. J. R. Heck· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersImmunology

C. G. Figdor

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Author profile →

2 papers

Recent·Most cited

Efficient targeting of NY-ESO-1 tumor antigen to human cDC1s by lymphotactin results in cross-presentation and antigen-specific T cell expansion

C. M. Le Gall, A. Cammarata, L. de Haas, I. Ramos-Tomillero, J. Cuenca-Escalona, Z. Wijfjes, A. M. D. Becker, Y. Dolen, I. J. M. de Vries, C. G. Figdor, G. Florez-Grau, M. Verdoes

This study demonstrates that targeting NY-ESO-1 antigen to human cDC1s via XCL1(CC3) enhances cross-presentation and CD8+ T cell activation.

bioRxiv · Nov 30, 2021Immunology

Functional diversification of hybridoma produced antibodies by CRISPR/HDR genomic engineering

J. M. S. van der Schoot, F. L. Fennemann, M. Valente, Y. Dolen, I. M. Hagemans, A. M. D. Becker, C. M. Le Gall, D. van Dalen, A. Cevirgel, J. A. C. van Bruggen, M. Engelfriet, M. F. Fransen, T. Caval, A. E. H. Bentlage, M. Nederend, , F. A. Scheeren

This study presents a CRISPR/HDR platform to engineer hybridoma antibodies for diverse isotypes, formats, and species, enabling functional antibody diversification.

bioRxiv · Feb 15, 2019Bioengineering