Author

A. E. H. Bentlage

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

G. Vidarsson· 3 shared A. Cevirgel· 1 shared A. J. R. Heck· 1 shared A. Lux· 1 shared A. M. D. Becker· 1 shared A. P. J. Vlaar· 1 shared A. R. Cruz· 1 shared Amsterdam UMC COVID-19 biobank study group· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

G. Vidarsson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Staphylococcal protein A inhibits IgG-mediated phagocytosis by blocking the interaction of IgGs with FcγRs and FcRn

A. R. Cruz, A. E. H. Bentlage, R. Blonk, C. J. C. d. Haas, P. C. Aerts, L. M. Scheepmaker, I. G. Bouwmeester, A. Lux, J. A. G. v. Strijp, F. Nimmerjahn, K. P. M. v. Kessel, G. Vidarsson, S. H. M. Rooijakkers

bioRxiv · Jan 21, 2022 · PreprintMicrobiology

Afucosylated immunoglobulin G responses are a hallmark of enveloped virus infections and show an exacerbated phenotype in COVID-19

M. D. Larsen, E. L. de Graaf, M. E. Sonneveld, H. R. Plomp, F. Linty, R. Visser, M. Brinkhaus, T. Sustic, S. W. deTaeye, A. E. H. Bentlage, J. Nouta, S. Natunen, C. A. M. Koeleman, S. Sainio, N. A. Kootstra, , G. Vidarsson

The paper shows that afucosylated IgG responses are common in enveloped virus infections and are more severe in COVID-19, with implications for immune response and pathology.

bioRxiv · May 18, 2020Immunology

Functional diversification of hybridoma produced antibodies by CRISPR/HDR genomic engineering

J. M. S. van der Schoot, F. L. Fennemann, M. Valente, Y. Dolen, I. M. Hagemans, A. M. D. Becker, C. M. Le Gall, D. van Dalen, A. Cevirgel, J. A. C. van Bruggen, M. Engelfriet, M. F. Fransen, T. Caval, A. E. H. Bentlage, M. Nederend, , F. A. Scheeren

This study presents a CRISPR/HDR platform to engineer hybridoma antibodies for diverse isotypes, formats, and species, enabling functional antibody diversification.

bioRxiv · Feb 15, 2019Bioengineering