Author

Y. Dolen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. M. D. Becker· 2 shared C. G. Figdor· 2 shared C. M. Le Gall· 2 shared J. Cuenca-Escalona· 2 shared M. Verdoes· 2 shared A. Cammarata· 1 shared A. Cevirgel· 1 shared A. E. H. Bentlage· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

A. M. D. Becker

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Galectin-9 regulates dendritic cell polarity and uropod contraction by modulating RhoA activity

G. Franken, J. Cuenca-Escalona, I. F. Stehle, V. van Reijmersdal, A. Rodgers Furones, R. R. Gokhale, R. Classens, S. diBlasio, Y. Dolen, A. van Spriel, L. Querol Cano

This study shows galectin-9 regulates dendritic cell migration by modulating RhoA activity and CD44-mediated rear contractility in both humans and mice.

bioRxiv · Oct 30, 2023 · PreprintImmunology

Efficient targeting of NY-ESO-1 tumor antigen to human cDC1s by lymphotactin results in cross-presentation and antigen-specific T cell expansion

C. M. Le Gall, A. Cammarata, L. de Haas, I. Ramos-Tomillero, J. Cuenca-Escalona, Z. Wijfjes, A. M. D. Becker, Y. Dolen, I. J. M. de Vries, C. G. Figdor, G. Florez-Grau, M. Verdoes

This study demonstrates that targeting NY-ESO-1 antigen to human cDC1s via XCL1(CC3) enhances cross-presentation and CD8+ T cell activation.

bioRxiv · Nov 30, 2021Immunology

Functional diversification of hybridoma produced antibodies by CRISPR/HDR genomic engineering

J. M. S. van der Schoot, F. L. Fennemann, M. Valente, Y. Dolen, I. M. Hagemans, A. M. D. Becker, C. M. Le Gall, D. van Dalen, A. Cevirgel, J. A. C. van Bruggen, M. Engelfriet, M. F. Fransen, T. Caval, A. E. H. Bentlage, M. Nederend, , F. A. Scheeren

This study presents a CRISPR/HDR platform to engineer hybridoma antibodies for diverse isotypes, formats, and species, enabling functional antibody diversification.

bioRxiv · Feb 15, 2019Bioengineering