Author

A. M. Morch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

M. L. Dustin· 3 shared A. M. Santos· 1 shared A. Patel· 1 shared A. Sakoguchi· 1 shared E. Jenkins· 1 shared E. M. Denham· 1 shared F. Schneider· 1 shared H. Arase· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersImmunology

M. L. Dustin

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Author profile →

3 papers

Recent·Most cited

RIFINs displayed on malaria-infected erythrocytes bind both KIR2DL1 and KIR2DS1

A. Sakoguchi, S. G. Chamberlain, A. M. Morch, T. E. Harrison, M. L. Dustin, H. Arase, M. K. Higgins, S. Iwanaga

The paper identifies RIFINs that bind both inhibitory and activating KIR receptors, revealing their role in modulating NK cell activation during malaria infection.

bioRxiv · Apr 30, 2024Microbiology

Using CombiCells, a platform enabling titration and combinatorial display of cell surface ligands, to study T cell antigen sensitivity by TCRs, CARs, and BiTEs

A. Patel, V. Andre, S. Bustamante Eguiguren, M. I. Barton, J. Burton, E. M. Denham, J. Pettmann, A. M. Morch, M. Kutuzov, J. A. Siller-Farfan, M. L. Dustin, P. A. van der Merwe, O. Dushek

The paper uses CombiCells to compare T cell antigen sensitivity mediated by TCRs, CARs, and BiTEs and assess the impact of co-stimulation and co-inhibition receptors.

bioRxiv · Jun 15, 2023 · PreprintImmunology

The kinase occupancy of T-cell coreceptors reconsidered

A. M. Morch, F. Schneider, E. Jenkins, A. M. Santos, S. E. Fraser, S. Davis, M. L. Dustin

The paper re-evaluates kinase occupancy of T-cell coreceptors CD4 and CD8β, finding CD4-Lck interaction is stoichiometric while CD8β-Lck is substantial, with structural differences influencing binding.

bioRxiv · Aug 1, 2022Immunology