Author

J. Hope

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:chicken / avian· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J. Stevens· 2 shared K. Jensen· 2 shared P. Cherepanov· 2 shared R. Blake· 2 shared A. Fung· 1 shared A. H. M. van Vliet· 1 shared A. McKnight· 1 shared A. Nans· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

J. Stevens

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Preservation of memory B cell homeostasis in an individual producing broadly neutralising antibodies against HIV-1

S. Griffith, L. Muir, O. Suchanek, J. Hope, C. Pade, J. M. Gibbons, Z. K. Tuong, A. Fung, E. Touizer, C. Rees-Spear, A. Nans, C. Roustan, Y. Alguel, D. Fink, C. Orkin, , L. E. McCoy

The paper isolates a broadly neutralizing HIV-1 antibody from an untreated HIV-1 patient and shows memory B cells remain functional despite viral infection.

bioRxiv · Feb 5, 2024 · PreprintMicrobiology

Investigating the role of Mce proteins in Mycobacterium avium paratuberculosis infection

R. Blake, K. Jensen, O. Alfituri, N. A. Mabbott, J. Hope, J. Stevens

This study identifies Mce1A and Mce1D as effector molecules in MAP that enhance bacterial attachment and invasion in specific cell types.

bioRxiv · Jun 6, 2023 · PreprintMicrobiology

The immune response to lumpy skin disease virus in cattle is influenced by inoculation route

P. C. Fay, N. Wijesiriwardana, H. Munyanduki, B. Sanz-Bernardo, I. Lewis, I. R. Haga, K. Moffat, A. H. M. van Vliet, J. Hope, S. Graham, P. Beard

This study compares immune responses in cattle inoculated with LSDV via needle or arthropod vectors, finding differences in clinical disease development and immune markers like IgM and IFN-γ.

bioRxiv · Sep 22, 2022Immunology

Development of 3D bovine intestinal organoid derived models to investigate Mycobacterium avium ssp paratuberculosis pathogenesis

R. Blake, K. Jensen, N. Mabbott, J. Hope, J. Stevens

This study develops 3D bovine intestinal organoid models to study Mycobacterium avium ssp. paratuberculosis infection and finds that C49 is more invasive than K10 in these models.

bioRxiv · May 13, 2022 · PreprintMicrobiology

Favourable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases

C. Deakin, G. Cornish, K. Ng, N. Faulkner, W. Bolland, V. Panova, J. Hope, A. Rosa, R. Harvey, S. Hussain, C. Earl, B. Jebson, M. Wilkinson, L. Marshall, K. O'Brien, , G. Kassiotis

The paper examines antibody responses to HCoV-OC43 and SARS-CoV-2 in children with autoimmune rheumatic diseases, finding stronger spike antibody responses and cross-reactivity despite immunosuppressive treatment.

bioRxiv · Feb 15, 2021 · PreprintImmunology