Author

A. Muralidharan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Immunology· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. C. Fluit· 1 shared A. C. Haagsma· 1 shared A. L. Smith· 1 shared A. R. Costa· 1 shared A. Vahid· 1 shared A. Yethiraj· 1 shared B. A. van der Steen· 1 shared B. Estrada Bonilla· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperMicrobiology

A. C. Fluit

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Author profile →

6 papers

Recent·Most cited

Accumulation of defense systems in phage resistant strains of Pseudomonas aeruginosa

A. R. Costa, D. F. van den Berg, J. Q. Esser, A. Muralidharan, H. van den Bossche, B. Estrada Bonilla, B. A. van der Steen, A. C. Haagsma, A. C. Fluit, F. L. Nobrega, P.-J. Haas, S. J. Brouns

The paper shows that Pseudomonas aeruginosa strains with more phage defense systems are more resistant to phages, and these systems often target different phage genera.

bioRxiv · Aug 12, 2022 · PreprintMicrobiology

Intracellular transport of electrotransferred DNA cargo is governed by coexisting ergodic and non ergodic anomalous diffusion

A. Muralidharan, H. Uitenbroek, P. E. Boukany

This study investigates DNA cargo transport in mammalian cells after electrotransfer, finding coexisting ergodic and non-ergodic anomalous diffusion, with transport properties dependent on DNA size and cell type.

bioRxiv · Apr 12, 2021 · PreprintBiophysics

Bromodomain and Extraterminal Protein Inhibitor, Apabetalone (RVX-208), Reduces ACE2 Expression and Attenuates SARS-CoV-2 Infection in vitro

D. Gilham, A. L. Smith, L. Fu, D. Y. Moore, A. Muralidharan, S. P. M. Reid, S. C. Stotz, J. O. Johansson, M. Sweeney, N. C. Wong, E. Kulikowski, D. El-Gamal

This study shows apabetalone reduces ACE2 and DPP4 expression and inhibits SARS-CoV-2 infection in vitro, suggesting it could be a potential therapeutic for COVID-19.

bioRxiv · Mar 10, 2021Pharmacology & Toxicology

A solvation induced ring puckering effect in fluorinated prolines and its inclusion in classical force-fields

A. Muralidharan, J. R. Schmidt, A. Yethiraj

The paper investigates solvation effects on fluorinated proline ring puckering using electronic structure calculations and develops a force-field correction to model these effects accurately.

bioRxiv · May 11, 2020Biophysics

Unraveling the response of a biomimetic actin cortex to electric pulses in vesicles

D. Perrier, A. Vahid, V. Kathavi, L. Stam, L. Rems, Y. Mulla, A. Muralidharan, G. Koenderink, M. Kreutzer, P. Boukany

This study examines how an actin cortex in giant unilamellar vesicles affects electroporation and membrane resealing in response to electric pulses.

bioRxiv · Jun 7, 2019 · PreprintBiophysics

Identification and Characterisation of the CD40-Ligand of Sigmodon hispidus

X. Li, M. Russell, L. Larocque, J. Cao, Y. Deschambault, J. Varga, s. N. Thulasi Raman, a. muralidharan

This study clones and characterizes the CD40 ligand in cotton rats, showing its functional activity on dendritic cells and potential utility in immunological research.

bioRxiv · Jun 1, 2018Immunology