Author

A. R. Costa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Approach:microscopy & imaging analysis· 2 Assay:whole-genome sequencing· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1

Frequent Co-Authors

B. Estrada Bonilla· 2 shared F. L. Nobrega· 2 shared P.-J. Haas· 2 shared S. J. Brouns· 2 shared A. BriegeliD· 1 shared A. C. Almeida· 1 shared A. C. Fluit· 1 shared A. C. Haagsma· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

B. Estrada Bonilla

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

High resolution reconstruction of a Jumbo bacteriophage infecting capsulated bacteria using hyperbranched tail fibers

R. Ouyang, A. R. Costa, C. K. Cassidy, A. Otwinowska, V. C. J. Williams, A. Latka, P. J. Stansfeld, Z. J. Drulis-Kawa, Y. Briers, D. M. Pelt, S. J. J. Brouns, A. Briegel

This study determines the high-resolution structure of a jumbo bacteriophage infecting Klebsiella pneumoniae, revealing its complex tail fibers that enable infection of multiple capsular polysaccharide types.

Nature Communications · Nov 24, 2022Peer-reviewedMicrobiology

Accumulation of defense systems in phage resistant strains of Pseudomonas aeruginosa

A. R. Costa, D. F. van den Berg, J. Q. Esser, A. Muralidharan, H. van den Bossche, B. Estrada Bonilla, B. A. van der Steen, A. C. Haagsma, A. C. Fluit, F. L. Nobrega, P.-J. Haas, S. J. Brouns

The paper shows that Pseudomonas aeruginosa strains with more phage defense systems are more resistant to phages, and these systems often target different phage genera.

bioRxiv · Aug 12, 2022 · PreprintMicrobiology

Genomic characterization of four novel bacteriophages infecting the clinical pathogen Klebsiella pneumoniae

B. Estrada Bonilla, A. R. Costa, T. van Rossum, S. Hagedoorn, H. Walinga, M. Xiao, W. Song, P.-J. Haas, F. L. Nobrega, S. J. Brouns

The paper isolates and sequences four novel bacteriophages infecting Klebsiella pneumoniae, revealing low sequence identity to known phages and potential new DNA packaging mechanisms and protein clades.

bioRxiv · Mar 2, 2021Microbiology

Coherent-hybrid STED: a tunable photo-physical pinhole for super-resolution imaging at high contrast

A. J. Pereira, M. Sousa, A. C. Almeida, L. T. Ferreira, A. R. Costa, M. Novais-Cruz, C. Ferras, M. M. Sousa, P. Sampaio, M. Belsley, H. Maiato

This paper introduces CH-STED, a super-resolution imaging technique that improves optical sectioning and reduces background fluorescence for high-contrast imaging of biological structures.

bioRxiv · Jul 31, 2018Biophysics

Genomic analysis of Acinetobacter baumannii prophages reveals remarkable diversity and suggests profound impact on bacterial virulence and fitness

A. R. Costa, R. Monteiro, J. Azeredo

This study analyzes Acinetobacter baumannii prophages to show their diversity and role in enhancing bacterial virulence and fitness.

bioRxiv · Mar 23, 2018Microbiology