Author

A. Muruato

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. L. Routh· 2 shared B. A. Johnson· 2 shared C. Schindewolf· 2 shared J. A. Plante· 2 shared K. Debbink· 2 shared K. S. Plante· 2 shared V. D. Menachery· 2 shared X. Xie· 2 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersMicrobiology

A. L. Routh

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mouse Adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge

A. Muruato, M. Vu, B. A. Johnson, M. Davis-Gardner, A. R. Vanderheiden, K. Lokugamage, C. Schindewolf, P. A. Crocquet-Valdes, R. M. Langsjoen, J. A. Plante, K. S. Plante, S. C. Weaver, K. Debbink, A. L. Routh, D. H. Walker, , V. D. Menachery

This study creates a mouse-adapted SARS-CoV-2 strain that protects mice from lethal SARS-CoV challenge, demonstrating cross-strain immunity.

bioRxiv · May 3, 2021Microbiology

Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis

B. A. Johnson, X. Xie, B. Kalveram, K. G. Lokugamage, A. Muruato, J. Zou, X. Zhang, T. Juelich, J. K. Smith, L. Zhang, C. Schindewolf, M. N. Vu, A. Vanderheiden, J. A. Plante, K. S. Plante, , V. D. Menachery

This study shows that removing the furin cleavage site from SARS-CoV-2 increases replication in Vero cells but reduces replication in respiratory cells and pathogenesis in hamsters, while also decreasing neutralization susceptibility.

bioRxiv · Aug 26, 2020 · PreprintMicrobiology