Author
B. Kalveram
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links6 papers
Recent·Most cited
Cross-neutralization and viral fitness of SARS-CoV-2 Omicron sublineages
H. Xia, J. Yeung, B. Kalveram, C. J. Bills, J. Y.-C. Chen, C. Kurhade, j. Zou, S. G. Widen, B. R. Mann, R. J. Kondor, T. C. Davis, B. Zhou, D. E. Wentworth, X. Xie, P.-Y. Shi
This study examines the replication and cross-neutralization of SARS-CoV-2 Omicron sublineages in mice and human airway cultures, finding distinct antigenic profiles and bivalent vaccine support.
bioRxiv · Nov 8, 2022Microbiology
Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis.
B. A. Johnson, Y. Zhou, K. G. Lokugamage, M. N. Vu, N. E. Bopp, P. A. Crocquet-Valdes, B. Kalveram, C. Schindewolf, Y. Liu, D. Scharton, J. A. Plante, X. Xie, P. Aguilar, S. Weaver, P.-Y. Shi, , V. D. Menachery
This study shows that mutations in the SARS-CoV-2 nucleocapsid protein enhance viral replication and pathogenesis by increasing phosphorylation and resisting kinase inhibition.
PLOS Pathogens · Jun 21, 2022Peer-reviewedMicrobiology
Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility
J. A. Plante, Y. Liu, J. Liu, H. Xia, B. A. Johnson, K. G. Lokugamage, X. Zhang, A. E. Muruato, J. Zou, C. R. Fontes-Garfias, D. Mirchandani, D. Scharton, J. P. Bilello, Z. Ku, Z. An, , P.-Y. Shi
This study shows the D614G mutation in SARS-CoV-2 increases viral replication and upper respiratory tract viral loads but does not reduce vaccine efficacy or antibody neutralization.
bioRxiv · Sep 1, 2020Microbiology
Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis
B. A. Johnson, X. Xie, B. Kalveram, K. G. Lokugamage, A. Muruato, J. Zou, X. Zhang, T. Juelich, J. K. Smith, L. Zhang, C. Schindewolf, M. N. Vu, A. Vanderheiden, J. A. Plante, K. S. Plante, , V. D. Menachery
This study shows that removing the furin cleavage site from SARS-CoV-2 increases replication in Vero cells but reduces replication in respiratory cells and pathogenesis in hamsters, while also decreasing neutralization susceptibility.
bioRxiv · Aug 26, 2020 · PreprintMicrobiology
Peptidoglycan associated cyclic lipopeptide disrupts viral infectivity
B. A. Johnson, A. Hage, B. Kalveram, M. Mears, J. A. Plante, S. E. Rodriguez, Z. Ding, X. Luo, D. Bente, S. S. Bradrick, A. N. Freiberg, V. Popov, R. Rajsbaum, S. Rossi, W. K. Russell, V. D. Menachery
The paper identifies surfactin, a cyclic lipopeptide from bacterial peptidoglycan, as a broad-spectrum virucidal compound that disrupts enveloped virus infectivity.
bioRxiv · May 13, 2019Microbiology