Author

A. P. Bravos

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Biochemistry· 1

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

C.-G. Wu· 1 shared I. V. Novikova· 1 shared M. Rowse· 1 shared S. Strack· 1 shared V. K. Balakrishnan· 1 shared V. K. Yadav· 1 shared Y. Ivarsson· 1 shared Y. Li· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

C.-G. Wu

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1 paper

Recent·Most cited

Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition

Y. Li, V. K. Balakrishnan, M. Rowse, C.-G. Wu, A. P. Bravos, V. K. Yadav, Y. Ivarsson, S. Strack, I. V. Novikova, Y. Xing

This study shows PME-1 demethylates PP2A holoenzymes and inhibits substrate recognition through structural interactions with the B56 subunit, revealing mechanisms of PME-1 activity and its role in p53 signaling.

bioRxiv · Jul 1, 2022Biochemistry