Author

V. K. Yadav

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

Y. Ivarsson· 3 shared A. Behren· 1 shared A. Clemenceau· 1 shared A. Corvelo· 1 shared A. Khramushin· 1 shared A. P. Bravos· 1 shared A.-C. Gingras· 1 shared B. Pal· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersBiochemistry

Y. Ivarsson

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The circulating immune cell landscape stratifies metastatic burden in breast cancer patients

S. Mangiola, R. Brown, J. Berthelet, S. Guleria, C. Liyanage, S. Ostrouska, J. Wilcox, M. Merdas, P. F. Larsen, C. Bell, J. Schroder, L. Mielke, J. Mariadason, S. Chang-Hao Tsao, Y. Chen, , B. Pal

This study identifies immune cell signatures in peripheral blood that correlate with metastatic burden in breast cancer patients using single-cell transcriptomics.

bioRxiv · Nov 1, 2023 · PreprintCancer Biology

Osteocalcin of maternal and embryonic origins synergize to establish homeostasis in offspring

D. Correa Pinto, I. Canal Delgado, H. Yang, A. Clemenceau, A. Corvelo, G. Narzisi, R. Musunuri, J. Berger, L. Hendricks, K. Tokumura, N. Luo, H. Li, F. Oury, P. Ducy, V. K. Yadav, , G. Karsenty

This study shows maternal and embryonic osteocalcin work together to maintain homeostasis in offspring by affecting insulin secretion, glucose metabolism, and steroidogenesis.

bioRxiv · Aug 11, 2023 · PreprintPhysiology

Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition

Y. Li, V. K. Balakrishnan, M. Rowse, C.-G. Wu, A. P. Bravos, V. K. Yadav, Y. Ivarsson, S. Strack, I. V. Novikova, Y. Xing

This study shows PME-1 demethylates PP2A holoenzymes and inhibits substrate recognition through structural interactions with the B56 subunit, revealing mechanisms of PME-1 activity and its role in p53 signaling.

bioRxiv · Jul 1, 2022Biochemistry

Short linear motif based interactions and dynamics of the ezrin, radixin, moesin and merlin FERM domains

M. Ali, A. Khramushin, V. K. Yadav, O. Schueler-Furman, Y. Ivarsson

The paper identifies and characterizes short linear motifs binding to FERM domains of ERM proteins and merlin, revealing allosteric regulation between ligands.

bioRxiv · Nov 23, 2020 · PreprintBiochemistry

Systematic discovery of Short Linear Motifs decodes calcineurin phosphatase signaling

C. P. Wigington, J. Roy, N. P. Damle, V. K. Yadav, C. Blikstad, E. Resch, C. J. Wong, D. R. Mackay, J. T. Wang, I. Krystkowiak, D. A. Bradburn, E. Tsekitsidou, S. H. Hong, M. A. Kaderali, S.-l. Xu, , M. S. Cyert

The paper identifies calcineurin (CN) substrates and interactors using a combination of experimental and computational methods, revealing novel roles for CN in regulating nuclear pore complex proteins.

bioRxiv · Mar 26, 2020Cell Biology