Author

A. Pugliese

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:mouse· 1

Frequent Co-Authors

A. Carre· 1 shared A. L. Posgai· 1 shared A. Long· 1 shared B. Brandao· 1 shared C. Bustamante· 1 shared C. Evans-Molina· 1 shared C. Halliez· 1 shared C. Yang· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperImmunology

A. Carre

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Coxsackievirus infection induces direct pancreatic β-cell killing but poor anti-viral CD8+ T-cell responses

F. Vecchio, A. Carre, D. Korenkov, Z. Zhou, P. Apaolaza, S. Tuomela, O. Burgos-Morales, I. Snowhite, J. Perez-Hernandez, B. Brandao, G. Afonso, C. Halliez, J. Kaddis, S. C. Kent, M. Nakayama, , R. Mallone

This study shows that Coxsackievirus B directly kills pancreatic β-cells and elicits weak CD8+ T-cell responses, suggesting vaccination could prevent type 1 diabetes.

bioRxiv · Aug 19, 2023 · PreprintImmunology

ACE2 and SARS-CoV-2 Expression in the Normal and COVID-19 Pancreas

I. Kusmartseva, W. Wu, F. Syed, V. van der Heide, M. Jorgensen, P. Joseph, X. Tang, E. Candelario-Jalil, C. Yang, H. Nick, J. Harbert, A. L. Posgai, R. Lloyd, S. Cechin, A. Pugliese, , M. A. Atkinson

This study examines ACE2 and SARS-CoV-2 expression in normal and COVID-19 pancreas tissues, finding prominent ACE2 expression in ductal epithelium and microvasculature, with limited endocrine cell expression and no strong evidence of SARS-CoV-2 infection of endocrine cells.

bioRxiv · Aug 31, 2020 · PreprintPathology

Sustained Release of IL-2 Using an Injectable Hydrogel Prevents Autoimmune Diabetes

N. Nagy, G. Kaber, M. Kratochvil, H. Kuipers, S. Ruppert, K. Yadava, J. Yang, S. Heilshorn, A. Long, A. Pugliese, P. Bollyky

This paper develops an IL-2 hydrogel that prevents diabetes in NOD mice by sustained release and immune modulation.

bioRxiv · Mar 15, 2020 · PreprintImmunology