A. Rosenthal

The multi-Siglec inhibitor AL009 reprograms suppressive macrophages and activates innate and adaptive tumor immunity

AL009, a multi-Siglec inhibitor, reprograms suppressive macrophages and enhances anti-tumor immunity in preclinical models.

Metabolic fate of human immunoactive sterols in Mycobacterium tuberculosis

The paper identifies Mtb enzymes that metabolize human immune oxysterols and vitamin D3 derivatives, revealing a potential drug target for tuberculosis treatment.

Prediction of multiple drug resistant pulmonary tuberculosis against drug sensitive pulmonary tuberculosis by CT nodular consolidation sign

The paper identifies that multiple nodular consolidation signs on CT scans are more prevalent in multidrug-resistant and extensively drug-resistant pulmonary tuberculosis compared to drug-sensitive cases.

Integrated Low-Energy and Low Carbon Shortcut Nitrogen removal with Biological Phosphorus Removal for Sustainable Mainstream Wastewater Treatment

The paper demonstrates efficient combined nitrogen, phosphorus, and chemical oxygen demand removal in a wastewater treatment system using anaerobic-aerobic cycling and nitritation-denitritation without exogenous chemicals.

Microhomology-mediated end joining drives complex rearrangements and over expression of MYC and PVT1 in multiple myeloma

The paper identifies MYC rearrangements in multiple myeloma, showing they are complex and linked to overexpression of MYC and PVT1 through distinct DNA repair mechanisms.

Comammox Nitrospira are the dominant ammonia oxidizers in a mainstream low dissolved oxygen nitrification reactor

This study shows comammox Nitrospira dominate ammonia oxidation in a low dissolved oxygen nitrification reactor, outperforming conventional systems.