E. Marin

CryoRhodopsins: a comprehensive characterization of a group of microbial rhodopsins from cold environments

The paper characterizes CryoRhodopsins from cold environments, revealing their dual functionality and structural adaptations to low temperatures.

A novel subgroup of light-driven sodium pumps with an additional Schiff base counterion

The paper identifies a new subgroup of light-driven sodium pumps with an additional glutamic acid residue that reduces pH sensitivity for sodium transport.

Asparagine availability controls B cell homeostasis

The paper shows asparagine metabolism is critical for B cell function and germinal centre homeostasis, with Asn deprivation impairing survival, proliferation, and immune responses.

LAT1 enables T cell activation under inflammatory conditions: a new therapeutic target for rheumatoid arthritis

This study shows LAT1 is critical for T cell activation in rheumatoid arthritis and identifies it as a therapeutic target, with a LAT1 inhibitor effective in mouse models.

Structural insights into 3Fe-4S ferredoxins diversity in M.tuberculosis highlighted by a first redox complex with P450.

The paper solves the structures of 3Fe-4S ferredoxins from M. tuberculosis and their complex with CYP143, revealing structural and functional insights into redox interactions.

Structural basis for receptor selectivity and inverse agonism in S1P5 receptors

The paper presents a high-resolution structure of the S1P5 receptor complexed with an inverse agonist, revealing structural features that explain receptor subtype selectivity and inverse agonism.

Antibacterial 3D-printed PMMA/ceramic composites

This paper investigates 3D-printed PMMA/ceramic composites with antibacterial properties, finding that aluminum nitride provides the best dispersion and antibacterial effect against E. coli.

IL-22BP production is heterogeneously distributed in Crohn's disease

This study investigates IL-22BP production and distribution in Crohn's disease tissues, finding higher levels in ileum and associations with eosinophils, moDCs, and smoking.

A new twist of rubredoxin function in M. tuberculosis

This study identifies RubB as a cofactor for mycobacterial cytochrome P450s in M. tuberculosis, showing its role in bacterial survival and potential biotech applications.

Hydroxylation of antitubercular drug candidate, SQ109, by mycobacterial cytochrome P450

The paper shows that Mycobacterium tuberculosis CYP124 hydroxylates SQ109, a drug candidate, and potentially affects its interaction with MmpL3.

Metabolic fate of human immunoactive sterols in Mycobacterium tuberculosis

The paper identifies Mtb enzymes that metabolize human immune oxysterols and vitamin D3 derivatives, revealing a potential drug target for tuberculosis treatment.

Rapid Inactivation of SARS-CoV-2 by Silicon Nitride, Copper, and Aluminum Nitride

This study shows that silicon nitride, aluminum nitride, and copper inactivate SARS-CoV-2 by >99% within one minute, with silicon nitride being the most effective without causing cell damage.

Molecular mechanism of light-driven sodium pumping

The paper elucidates the molecular mechanism of Na+ pumping by KR2 rhodopsin using crystal structures and molecular dynamics, revealing a switching mechanism and structural similarities to channelrhodopsins.