Author

A. Sapmaz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Organism:zebrafish· 1

Frequent Co-Authors

H. Ovaa· 2 shared P. A. van Veelen· 2 shared P. P. Geurink· 2 shared A. Moutsiopoulou· 1 shared A. Pinto-Fernandez· 1 shared B. M. Kessler· 1 shared B.-T. Xin· 1 shared C. M. P. Talavera Ormeno· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiochemistry

H. Ovaa

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Development of covalent probes to capture Legionella pneumophila effector enzymes

G. J. van der Heden van Noort, M. S. Kloet, R. Mukhopadhyay, R. Mukherjee, M. Misra, M. Jeong, C. M. P. Talavera Ormeno, A. Moutsiopoulou, R. T. N. Tjokrodirijo, P. A. van Veelen, D. Shin, I. Dikic, A. Sapmaz, R. Q. Kim

The paper develops covalent probes to target Legionella pneumophila effector enzymes, demonstrating their effectiveness in capturing DupA through in vitro testing and structural analysis.

bioRxiv · Mar 19, 2024 · PreprintCell Biology

USP16 is an ISG15 cross-reactive deubiquitinase targeting a subset of metabolic pathway-related proteins

J. Gan, A. Pinto-Fernandez, D. Flierman, J. J. L. L. Akkermans, D. P. O'Brien, H. Greenwood, H. C. Scott, J. Neefjes, G. Fritz, K.-P. Knobeloch, H. van Dam, B. M. Kessler, H. Ovaa, P. P. Geurink, A. Sapmaz

This study identifies USP16 as an ISG15 cross-reactive deubiquitinase that regulates metabolic pathway-related proteins during type I interferon responses.

bioRxiv · Jun 26, 2023 · PreprintBiochemistry

A Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos

P. P. Geurink, R. Kooij, A. Sapmaz, S. Liu, B.-T. Xin, G. M. C. Janssen, P. A. van Veelen, P. ten Dijke, H. Ovaa

This paper develops a fluorescent small-molecule probe to monitor UCHL1 activity in live cells and zebrafish embryos, showing specificity for UCHL1 over other DUBs.

bioRxiv · Nov 1, 2019Biochemistry