Author

V. Sundaramurthy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

P. K. Vemula· 2 shared A. Chandra· 1 shared A. Guha· 1 shared A. H. Najar· 1 shared A. Majumdar· 1 shared A. Sasmal· 1 shared A. Singh· 1 shared A. Varki· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersPathology

P. K. Vemula

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Niacinamide enhances cathelicidin mediated SARS-CoV-2 membrane disruption

T. Bhatt, S. U. Khedkar, B. Dam, S. Lall, S. Pandey, S. Kataria, P. M. Dias, M. Waskar, J. Raut, V. Sundaramurthy, P. K. Vemula, N. Ghatlia, A. Majumdar, C. Jamora

This study shows niacinamide enhances LL37's ability to disrupt SARS-CoV-2 membranes, suggesting it could improve AMP-based therapies for COVID-19.

Frontiers in Immunology · Nov 8, 2023Peer-reviewedPathology

Acidosis, Zinc and HMGB1 in Sepsis: A Common Connection Involving Sialoglycan Recognition

S. S. Siddiqui, C. Dhar, V. Sundaramurthy, A. Sasmal, H. Yu, E. Bandala-Sanchez, M. Li, X. Zhang, X. Chen, L. C. Harrison, D. Xu, A. Varki

This study shows that HMGB1 is sequestered by plasma sialoglycoproteins at physiological pH but is released during sepsis when pH and zinc levels drop, leading to immune activation.

Proceedings of the National Academy of Sciences · Mar 3, 2021Peer-reviewedImmunology

Niclosamide inhibits SARS-CoV2 entry by blocking internalization through pH-dependent CLIC/GEEC endocytic pathway

C. Prabhakara, R. Godbole, P. Sil, S. Jahnavi, T. S. van Zanten, D. Sheth, N. Subhash, A. Chandra, V. K. Nuthakki, T. P. Puthiyapurayil, R. Ahmed, A. H. Najar, S. M. Lingamallu, S. Das, B. Mahajan, , S. Mayor

bioRxiv · Dec 16, 2020Cell Biology

Robust lysosomal rewiring in Mtb infected macrophages mediated by Mtb lipids restricts the intracellular bacterial survival

K. Sachdeva, M. Goel, M. Sudhakar, M. Mehta, R. Raju, K. Raman, A. Singh, V. Sundaramurthy

The paper shows that Mtb lipids induce lysosomal rewiring in infected macrophages, enhancing host defense and restricting bacterial survival.

bioRxiv · Nov 29, 2019Cell Biology