Author

A. Senabouth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:scRNA-seq· 3 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

J. Powell· 3 shared A. Murphy· 1 shared A. Pebay· 1 shared A. W. Hewitt· 1 shared B. Leavers· 1 shared C. J. A. Smith-Anttila· 1 shared D. Amann-Zalcenstein· 1 shared D. C. Kaczorowski· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

J. Powell

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Protein Translation Dysregulation and Immune Cell Evasion Define Metastatic Clones in HPV-related Cancer of the Oropharynx

V. Chin, W. Muskovic, R. A. McCloy, D. Neavin, J. Alquicira, H. Arora, A. Senabouth, P. Keith, E. Spenceley, A. Murphy, D. Kaczorowski, P. Floros, P. Earls, B. Leavers, J. Crawford, , J. Powell

This study identifies mechanisms of immune evasion and metastasis in HPV-related oropharyngeal cancer using single-cell and spatial genomic data, showing dysregulated protein translation and immune pathway suppression in metastatic clones.

bioRxiv · Apr 15, 2024 · PreprintCancer Biology

Evolving Transcriptomic Signature of Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cells With Age

G. E. Lidgerwood, A. Senabouth, C. J. A. Smith-Anttila, V. Gnanasambandapillai, D. C. Kaczorowski, D. Amann-Zalcenstein, E. L. Fletcher, S. H. Naik, A. W. Hewitt, J. Powell, A. Pebay

This study characterizes the transcriptomic changes in hPSC-derived RPE cells over time in culture, showing a maturing transcriptional profile that resembles native RPE.

bioRxiv · Jul 26, 2020Cell Biology

Detection of HPV E7 transcription at single-cell resolution in epidermis

S. Lukowski, K. Tuong, K. Noske, A. Senabouth, Q. Nguyen, P. Soyer, I. Frazer, J. Powell

The paper uses scRNA-seq to detect HPV16-E7 mRNA in mouse keratinocytes, showing its association with gene expression and potential for identifying HPV involvement in cancer.

bioRxiv · Jan 24, 2018Cell Biology